Contains Insect Growth Regulator (IGR) to kill flea eggs and prevent reinfestation. Each applicator kills and repels fleas, ticks, and mosquitoes for up to 30 days. Features the Pet Specifix Applicator and Accu-Tip Dispenser. A flea control for dogs. (over 60 lbs.) kills and repels fleas ticks and mosquitoes for up to 30 days. Kill flea eggs to prevent reinfestation. Apply 1/3 of applicator to base of dogs neck. Apply 1/3 to the middle of back and apply the remaining 1/3 to the base of dogs tail. Permethrin (45%) (S)-Methoprene (3%) Other Ingredients (52%): Size: Large OVER 60lb.