UP4 leading We've been making probiotics in the USA since 1979. And it's all we do, from creating the formulas and manufacturing to getting our products to you. For us, it's a science, an art and definitely our passion. UP4 science Not all probiotic strains are created equal. We start with exceptionally resilient, scientifically validated strains like Lactobacillus acidophilus DDS-1 as a base for all of our formulas. We add additional live cultures that can naturally withstand stomach acid and bile without the need for chemical coatings. UP4 health Our formulas are based on the researched and proven strains that promote the healthy bacteria in your body. With probiotics and your body in balance, the results are a happier inside. UP4 trust We stand on our legacy of quality. We're dedicated to being a leader in the field and guarantee you will always get what is promised on our label. It's what you'd expect from a company that's all in for probiotics. leading scientific healthy trusted Laboratory tested to meet strict standards for potency and identity.