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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #38 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,415 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5415)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Danielle L.
New Orleans, LA
11 reviews
I have suffered from extremely bad sinus headaches for over 7 years. Tylenol extra strength is the only over the counter medicine that has ever helped relieve my headaches! I honestly do not know what I would do without it.
Gisela M.
Tulsa, OK
106 reviews
Wellness Guru Expert Level 1
Edna G.
Glendale, NY
118 reviews
Wellness Guru Expert Level 2
You can never go wrong with standard Tylenol. I carry this little bottle with me especially if I'm traveling. You never know when you'll need it. I mainly use it for body aches, it doesn't work for me when I have headaches.
Aubriana D.
22 reviews
I would recommend this product for anyone that has a headache or minor pain. This product is great at delivering pain fast! In my opinion I have never had any problems with this medication and would definitely buy this item again. I feel like it is affordable when you’re comparing it to Excedrin Migraine Pain Reliever Geltabs, 20 ea or other pain reliever.
Kelsey B.
294 reviews
Wellness Guru Expert Level 1
I always keep this in my purse! You never know when a migraine will unexpectedly pop up or cramps and this is always my go to. 10 full size pills which last me a decent time. Great price and very compact so it doesn’t take up a lot of space!
BriAnna 💀.
Resaca, GA
297 reviews
Wellness Guru Expert Level 1
Literally the worst pain medicine ever. I have severe chronic widespread pain(7+ years now) due to various chronic illnesses & autoimmune diseases, and this "extra strength" tylenol doesn't even begin to cut it. I remember before seeking treatment at doctors I was taking sooo many tylenol a day with no help, it was like I didn't even take anything. I'm sure this helps those with minor, mild aches and pains but definitely not severe or chronic pain. 
AnnaMaria F.
71 reviews
Works for headaches and backaches. I definitely recommend this. It helps me when I need it. It's affordable and majority of grocery stores and pharmacies carry this product. Tylenol® Extra Strength Caplets for Adults
Madeline J.
Mapleton, UT
189 reviews
I haven’t had any issues with these...ever. I don’t use them often, however, they are very effective. I like that I can use these for if I have cramps from ovarian cysts, or from working out really hard, or a migraine.
Mrs. L.
25 reviews
This seriously takes away the most annoying headaches! I take 2 of them and in about half and hour my headache is gone! This won't help with those suffering migraines..but any other headache, fever, pains this will do.
rose f.
42 reviews
I usually stray away from taking any kind of medication unless I feel miserable. I get really bad headaches and migraines. When I have a headache I just sleep it off. When I have a migraine I use this and it surprisingly does the job.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults