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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Megan N.
New Boston, IL
15 reviews
It works pretty well. I get shin splints a lot and this helps a bunch. It also helps alleviate my chronic migraines. This is usually the only kind of pain reliever I use because it's the one my mom always gave me and I don't trust anything else.
Keyana P.
Indianapolis, IN
120 reviews
Wellness Guru Expert Level 1
I am an avid tylenol user. I love the liquid Tylenol because it works much quicker than these pills do. Whenever I take them I’m not happy with how slow they are. Liquid Tylenol seems to do a much better job too. These are still in our medicine cabinet because we’ve ditched them for the liquid form! 
🌹 K.
27 reviews
Since I am a runner then I tend to get sore muscles all the time in my legs. And recently I had shin splints and was sore all day everyday. At night it was hard to sleep due to sore legs bothering me all night, so I would take Tylenol and it really seemed to help. So I would recommend this.
Salina P.
Louisburg, NC
101 reviews
I don't like taking pills for pain, unless the pain is really unbearable. I use extra strength Tylenol if my back is really killing me, I'm in excessive pain, or having really bad cramps. It works fast and does relieve my paint which is amazing. I would recommend trying or getting Tylenol Extra Strength if you need some pain relief ASAP. 
Becky S.
Depew, NY
41 reviews
I use this product often to help deal with back and neck pain. I purchased the product from our local food store, Wegmans. The product is a little pricy but does come with a lot and works really well so i would say that it was worth the money. I would recommend this product to anyone. 
Mitch A.
149 reviews
I rather take tynenol than other pain reliever peels i usually get stomach aches but these pills dont make me feel this way. I usually buy these at walmart or dollar general. So i recommend to anyone that has more of a sensitive stomach hopefully it helps anyone that might feel that way.
Sophear L.
San Leandro, CA
372 reviews
I always use Tylenol for pain relief! I actually have to keep this in stock because is the only medicine that work fast for my cramps! Without this medicine my cramps will keep me up all night! Not only it helps with cramps but my head ache too!
Shalimar H.
Fall River , MA
51 reviews
I only take Tylenol when my doctor tell me that I need to and I cannot take other than this. It is affordable and effective but I don't usually buy it or use it. Overall I'm satisfied with Tylenol. It is a good product just not my favorite.
Holly T.
Eastvale, CA
36 reviews
Love Tylenol Extra Strength! It works better and much more quickly than similar medicines! I often get terrible cramps and nothing ever helps - including medicine made specifically for cramps - but Tylenol Extra Strength helps every time!
Zariya G.
Chicago, IL
8 reviews
I use Tylenol when I have headaches or cramps. The pain is relieved within ten minutes. The price is affordable for what you get! I used to use Advil but decided to switch to Tylenol and this works much better! I am very satisfied with this product and would recommend it to anyone!
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults