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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Lemeka B.
Indian Head, MD
29 reviews
Tylenol is the only pain medicine that I can take due to a past condition. It gets the job done for me. Once I take the pills the pain is gone within an hour or two.
Alexus R.
Houston , TX
29 reviews
When I’m in so much pain I grab Tylenol extra strength’ for all my pain I take two capsules for what ever pain I have and within a couple minutes all my pain is gone
Taylor A.
106 reviews
I have frequent severe migraines and when it’s that time of the month, severe cramps. Tylenol extra strength is the only thing that helps my pain. Love this stuff!!
Lauren A.
Mount Vernon, IA
949 reviews
Wellness Guru Expert Level 2
This works well for when I’m having period cramping or headaches. The price is reasonable and always works well for me. I typically have some in my medicine cabinet.
Theresa A.
84 reviews
Works great for fevers and related aches and pains. I don’t really use this product aside from when I’m sick, but I’m sure the effects are similar for everyday aches.
adree k.
146 reviews
Wellness Guru Expert Level 2
This is what has gotten me through recovering from 2 c-section. I get off the prescription pain killers as fast as possible and use this to manage pain when I go home from the hospital.
Isui G.
Los Angeles, CA
128 reviews
I know I can always rely on Tylenol when I'm sick, with a migraine or muscle soreness. I have some in my work bag, first aid kit box, and bathroom medicine cabinet
Whitney W.
Fort Worth, TX
40 reviews
I have used Tylenol ever since I can remember. It has helped everything from my migraines to sore muscles! I don't trust any other pain relief to get the job done!
Stephanie H.
24 reviews
Helps with my very bad migraines and makes them go away within 30 minutes so I can move on with things that I would not be able to get done without having done it
Lauren E.
Millington, TN
57 reviews
These are always in our home in every car we own they are always there we are a active family we don’t want a little ache or pain to get us down this product is quick on the relief
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults