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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Chantelle B.
48 reviews
Tylenol is my GO TO GUY. I used take Advil liquid gels but after being in the hospital a couple times I realized Tylenol is what I always took I just get to it!
Tasha A.
108 reviews
I don't find Tylenol to be very effective in general. I will use it in a pinch if I have nothing else and it will take the edge off so I can be somewhat functio
Fiorentina C.
104 reviews
Yo amo estas pastillas son mi salvación cada vez que tengo dolor de cabeza actúan rápido pero es necesario tomar las 2 tabletas si no no hacen el mismo efecto
Nicole Marie R.
Whitby, ON
282 reviews
Wellness Guru Expert Level 2
I do not know what I would do without Tylenol! It helps reduce pain whether it be muscle or head. I fine it's easily accessible as well at all different stores
Audrey-Anne L.
Québec, QC
15 reviews
Tylenol always have my back when I don't feel great. Headache, muscle pain, back pain...it really works well and doesn't affect my stomach like Advil would do
Ana V.
Santo Domingo
69 reviews
Es un excelente medicamento para aliviar los dolores musculares. Se encuentra fácil en todas las farmacias y es de venta sin receta. Me funciona bastante bien. 
Tylenol, es el medicamento favorito de los pacientes que atiendo en mi trabajo; ya que les alivia los síntomas como el dolor de cabeza, que son tan molestos.
Angela G.
33 reviews
I'm a kidney donor, so I'm only able to take Tylenol products as it's less harsh on my leftover kidney, it's always effective and relieves my aches and pains
Jessica H.
6 reviews
These are the perfect purse-sized secret weapon for tension headaches, muscle pain and sore back during those long days when you're constantly on your feet.
Shelly L.
23 reviews
Does nothing for me, it's almost like eating sugar candy.  I won't take any more than two at a time but I don't find they work as well as Advil at all.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults