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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Karla L.
93 reviews
Wellness Guru Expert Level 1
I like it it's effective and fast wich is more important i feel satisfied one of my favorite brands is tylenol, i use it a lot maybe too much always works, even with horrible headaches that i sufer 
Ava B.
Kingscliff , NSW
40 reviews
When I had my concussion last year that kept me out of school and work for 8 months I took these and it helped me to be able to leave my house when I had a migraine. Super great for headaches I love it.
Leann E.
Macklin, SK
27 reviews
After 30+ years of migraines, i cant imagine life without Tylenol extra strength in it! It has been a significantpart of my pain management for ages and a vital necessity to get thru my worst headaches.
Corabelle B.
6 reviews
I don't necessarily take it all the time, because I usually tough it out. But if it is really bad and can't handle the pain this is the product I reach for and would recommend
Ana Patricia M.
santo domingo
91 reviews
I like this product i buy it in the store and drugstore its cheap and helps me release the pain i used for my period pain and my back pain its great and work for headaches to
Holly E.
Calgary, AB
170 reviews
Wellness Guru Expert Level 1
I recently used these, they do the trick for sure - however I have trouble swallowing pills so I prefer Tylenols EZ tablets, they are smaller and coated so they taste a bit better and go down smoother.
Athena G.
Kentville, NS
86 reviews
I take Tylenol only when I absolutely have to. I find that if I take it often then the product does not work to cure the issue. My boyfriend swears by them though so they are always in our cabinet
Mrrrr G.
563 reviews
Absolutely great product that definitely gets the job done when I need it to. Works amazingly fast as well. Always make sure to carry it around with me in case I need it. Highly recommend to everyone that needs it! Great!
Nathaly A.
45 reviews
I really use Tylenol for any kind of discomfort, I think it covers a lot of spectrum and can influence both body discomfort and headaches. For what I consider to be a quite versatile medicine
Amanda B.
3 reviews
Works good for headaches but with any pills If you take it too often it loses its effect but works if interchanged with other pills and gets the job done gets rid of headaches fast affordable I think compared to other products works well I like it would reconnect 
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults