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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,416 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5416)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
M S.
49 reviews
My go to for any kind of pain, one or two pills are like magic, stronger than its other competitors and very affordable and available at any pharmacy. Tylenol® Extra Strength Caplets for Adults
Taylor M.
North Bay
23 reviews
I’ve never had a bad experience with Tylenol. Whenever I get bad cramps or a bad headache Tylenol always helps me ease the pain. I will definitely buy Tylenol again and would recommend this product to others.
Mariela P.
Miami, FL
106 reviews
This is an excellent medication and it does not require a prescription from a doctor; however, I would recommend consulting a physician before using 500 MG tablets on a regular basis.
Rebeca D.
San Ysidro, CA
611 reviews
Wellness Guru Expert Level 1
My dad always gives me this medicine when I feel like I have the flu and I think that this pills are effective, I feel so much better when I take one. I usually buy them at the drugstore or the supermarket.
Heidi A.
25 reviews
Even though it is extra strength it doesn't take the pain away. It may take the edge off but not the dull pain. I wish it would work as I can only have pain killers with acetaminophen due to health problems
Dana L.
Alliston , ON
4 reviews
I find, in most cases, I only need to take one for my migraines.  The pain usually goes away within 30 minutes. For extreme migraines, I may need to take a second tablet.  Tylenol is always available somewhere for a good price.  Tylenol is my "go to" brand for pain releif
Ishita D.
399 reviews
It’s a really important medicine. I use it whenever I’m in distress. It’s affordable i guess. Yes it is very effective. Didn’t disappoint me at all. I use it every so often. Yes i do recommend it to my fellow people
Aglaé V.
9 reviews
Effective, effective, effective. It's all I can say, I love the product every time I use it. It's abordable, and sooo effective! For pain relief, headaches or menstrual pain. I always have a bottle at home
Rina R.
95 reviews
Tylenol always helps get rid of my headaches and sore body but too much of it is obviously not great for your liver - a hot bath and a nap can both be alternatives to relieve headaches and sore body parts
Ashley J.
Murray, KY
66 reviews
Tylenol is my go to for all my achs and pains. I could not functions some days without it. I take 2 and I can go on with my day. It helps with my joint pain from a chronic illness so Tylenol is my friend.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults