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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #38 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,415 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5415)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Eva Maria N.
1603 N.W. 79 Ave
168 reviews
Because I have a very sensitive stomach this is the only product I can safely take for my Arthritis. I have tried other products, even prescriptions that have antacids in them but atfer a week or so, I begin to have severe stomach pains. Tylenol is the only pill that relieves most of my pain withhout causing intesinal pain. I know it is not the strongest drug for joint pain, but it does keep it under control enough that I can continue with an active lifestyle. i would not know what to do without it. And the regular Tylenol would work in a pinch, but you would have to take it too often during the day and night. This pill lasts 8 hours and needs to be taken only twice a day. Also, I would warn users to be careful of their alcohol intakie also, when taking Tylenol.
🧡🧡 C.
73 reviews
this is by far the best pain reliever and works more or less instantly!
best thing for my headaches that i sometimes get at work 😭
i prefer the capsules over the tablets as i personally think they are easier to swallow
Megan L.
Holyrood , NL
149 reviews
Love love this product. It has worked very well for me so far at a very reasonable and affordable price point. I would for sure but this product again to use , and I would highly recommended this to family and friends to use !
Barbie A.
Tangerang selatan
34 reviews
This is a life saver for me! I can't use Advil or aspirin so Tylenol helps me on my days where I'm in need of a pain reliever. The extra strength helps knock out my symptoms in less than an hour. I always stick up on the jumbo bottles.
Sadaf K.
Dubai, Dubai
33 reviews
Tylenol is like a super pill! Once instant you are having a bad headache, you pop one Tylenol and the next instant, the headache is gone! It is definitely pricey but totally worth every penny. I bought a big 200 count bottle form Costco this May and since then it's my go to medicine for instant pain relief.
Delmy B.
Miami, FL
182 reviews
Es muy bueno y efectivo, hace efecto rápido y por su precio vale la pena probarlo utilizar en cualquier tipo de dolor malestar general lo puedes encontrar en cualquier lugar cualquier farmacia supermercado en las tiendas
Morgan S.
29 reviews
Headaches and overall body pain I find the extra strength to work the best. Only takes about 20 minutes before I can feel the headache going away, definitely effective. I don't have much to compare it to as I am loyal to Tylenol now a days. Overall I'm satisfied 
Catherine M.
Bishops Brae Avenue , Downpatrick
163 reviews
Is it weird to have a favourite painkiller? I suffer from endrometriosis and am frequently in pain. When it's really terrible I have prescription medications but when it's less severe I reach for Tylenol. It does so much better than any other over the counter painkillers, but unfortunately isn't sold in the Uk so I have to stock up when I'm in America whcjh luckily is one or two times per year.
Windsor, qc
52 reviews
Se produit en tout dans mon cas , est pour contrer la douleur légère ( ça fait la job ,mais  l'effet est longue à venir donc le secret pour assurer un soulagement pour la journée est de suivre la posologie maximale de 2 caplets 4 fois par jour . Mais comme j'ai dit seulement la douleur légère , il ne m'aide pas pour mes migraines ou autres douleurs plus sévères .  
Catherine L.
Quispamsis, NB
82 reviews
When I had surgery the hospital recommended taking Tylenol extra strength to maintain the pain. I didn't think it would do much and forgot my first day home, what a difference! As soon as it got back in my system (about 30 mins) I was feeling a thousand times better. Now Tylenol is my go to for all my headaches and pains.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults