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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Madison L.
748 reviews
Wellness Guru Expert Level 2
My family loves this product, super good quality and well priced for the value you get. Typically we buy most of our stuff at Walmart for a better price, but we can find stuff typically at any grocery store or pharmacy! our family will definitely continue to buy this awesome product!
Lynne L.
60 reviews
For a quality headache pill look no further than Tylenol Extra strength. I have trusted Tylenol grand for 40+ years. It almost always alleviates any headaches, toothaches or just general achy soreness. Highly recommended
Shanequa R.
28 reviews
Pain relievers are my best friend. I’m such a baby when it comes to pain. These are my go to for headaches, cramps , backache , every ache. Work very fast and a lot easier on your body then some other paint relievers.
paola a.
Calexico, CA
225 reviews
"It helps slightly but with Ehlers-Danlos and recurrent dislocations/subluxations it only helps a little if at all. It might help much more with minor conditions.Two 500 mg caplets taken at a time, 4 times a day. Did not work at all for my severe pain resulting from an abscessed tooth. Only got relief when using two 500 mg caplets of Bayer aspirin."
Jamie T.
134 reviews
This is a must have in the medicine cabinet. It always helps me out whenever I get really bad headaches. It’s a nice size, affordable and easy to swallow with a lot of water. I always have this stocked for everything
Mètis M.
Regina, SK
56 reviews
Tylenol always seems to do the trick when it comes to headache or any pains that I have! When I know Tylenol can't help than I should head to the doctor. It's very affordable and I 100 percent trust the brand.
Amber E.
Toronto, ON
145 reviews
Wellness Guru Expert Level 1
My go-to painkiller. Has always worked within 15 minutes or so. About a year ago I had gallstones and had to have my gallbladder removed and nothing took the pain away except Tylenol pre and post surgery.
Kristina K.
Vancouver, BC
57 reviews
I have a very high pain tolerance as well as a high resistance to painkillers so when I’m really in pain and I need something I turn to Tylenol and it really does the job. I find it way better than Advil
Stephanie C.
12 reviews
I use this product weekly. Mostly for headaches which I often get. I choose this product because it is easy on my stomach. Having had kidney problems in the past, tylenol seems to be the safest for me.
Krista S.
Channel, NL
86 reviews
This is now my go to OTC Pain reliever,
I usually take it for severe back and neck pain and headaches and it usually takes about 5-10 minutes until I feel better again.
Now don't mistake this for a drug that will take all the pain away but it will make it considerably less.
Iv taken Oxycodone, Percocet, and OxyContin, I can tell you this works nearly the same magic with less side effects.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults