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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Brianna L.
Sundre, AB
670 reviews
Wellness Guru Expert Level 4
I don’t know what it is about Tylenol but I’ve never had it work for me. The only painkiller that works for me is the good old avil liqui gels. Sorry Tylenol even these extra strength ones didn’t help me at all
Diana R.
Miami, FL
151 reviews
Unfortunately I suffer from headaches very often as I have a sensitive stomach and it always reflects into headaches. This is the only thing that cures my headaches. I cannot live without it and always carry a pack of 2 tablets 500 mg in my purse just in case a headache happens at the end of the day. I love this and it works for me. Additionally I think Ibuprofen does nothing to me so I am always inclined to products that contain acetaminophen. 
Ashley S.
Kemptville, ON
53 reviews
I cannot go anywhere without having this handy travel container with me. The funny thing is I rarely take medicine or Tylenol but when I need it I NEED it and this is so small and practical that it’s perfect to carry around. Highly recommend people purchase.
Erin P.
Strathroy, ON
175 reviews
Gives great relief from aches and pains after a long day at work. my job is physically demanding and this always helps me. I use tylenol probably about once or twice a week. It is effective. Please read instructions to find your appropriate dose.
Lindsey M.
Cambridge, ON
105 reviews
They do the trick and are an easy fix for a headache of slight muscle issues. They're available everywhere and it's something I've always got in my purse! They don't help for pain any higher than a 5 on a scale of 0-10 but good for simple things!
Yomna S.
Windsor, ON
276 reviews
I feel like Tylenol is too weak for me! It does not work for my physical pains or headaches at all. It's good for like minor pains, or when you don't wanna take too many strong drugs, like Advil is definitely stronger, but you don't wanna allow your body to just being used to one kind of painkiller! 
Nelia D.
64 reviews
While it takes a good hour to much in this my my number one med fir aches and pains. Formula won’t raise your blood pressure like Advil does do it’s safer to use fir the most of us especially us ppl who suffer from high blood pressure!
Shalee T.
50 reviews
Tylenol is something we constantly have in our house and I'm sure we go through it just as fast as we buy it. From chasing a toddler around the house all day, to walking the dog and working on our feet. It's a great back pain relief.
Alexia T.
98 reviews
I’ve only every had Tylenol extra strength and I only use it when I have head aches - not necessarily any other kind of body ache like cramps. I choose Advil for stuff like that. But for head aches, this stuff works magic.
Madison L.
748 reviews
Wellness Guru Expert Level 2
My family loves this product, super good quality and well priced for the value you get. Typically we buy most of our stuff at Walmart for a better price, but we can find stuff typically at any grocery store or pharmacy! our family will definitely continue to buy this awesome product!
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults