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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Melissa A.
Alexandria, VA
25 reviews
Wellness Guru Expert Level 2
I take two of these on the day that I have the worst menstrual cramps, and I don't need to take any more throughout the day.
Nikki G.
53 reviews
Tylenol is all I can take Advil makes my stomach hurt really bad. Tylenol is a great pain reliever especially for head aches
lizz c.
1684 reviews
Wellness Guru Expert Level 5
I always take this whwn i have a pain. Knocks out thw pain and really helps! Definitely always keep one in my bag and around.
Alexis H.
Edmond, OK
69 reviews
This product helps relieves my headaches within 20-30 minutes based on how severe my headache is. I would recommend to anyone
Bethany V.
Las Vegas, NV
125 reviews
Old faithful. Definitely helps with all my aches and pains including body aches and headaches. Not much more to say about it.
Amy M.
Holt, MI
72 reviews
Work immediately and never upset my stomach. Good for all of my aches and pains! Also safe to use for my teens' braces pain!
Micaela H.
Davison, MI
57 reviews
This is honestly the only thing that does the trick for me. No matter if it’s a headache, cramps, or injury, Tylenol does it!
Lacy S.
Evansville, IN
117 reviews
Tylenol is my preferred pain reliever. I take it whenever I have a headache and it almost always helps. 1000mg works wonders.
Amanda R.
148 reviews
Wellness Guru Expert Level 2
These work very fast for me and they are not to expensive I would rather buy thses over the off brand that dosent work well.
Anna S.
117 reviews
Wellness Guru Expert Level 1
Tylenol is my go-to during my period, if I'm having sinus pressure or headaches, or to alternate with ibuprofen when needed.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults