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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Brianna G.
130 reviews
Wellness Guru Expert Level 1
I love these they relieve my pain and it last hours unlike others I have tried the pills are not hard to swallow and it is easy to find these make me drowsy sometimes but they usually don’t and they don’t have a horrible powdery taste
Fallon C.
16 reviews
I'll be honest, I don't know that I can tell a difference between Tylenol, Advil and Aleve but when I have a headache/migraine the first thing I reach for is Tylenol (and I have all 3 on hand). Tylenol® Extra Strength Caplets for Adults
Elizabeth C.
Monroe, NC
17 reviews
Takes care of all of my pains and aches! I continue to be impressed with the effectiveness of Tylenol extra strength as well as how quickly it works. Within thirty minutes I can’t even remember what my minor pains and aches felt like.
Shayna B.
Bozeman, MT
25 reviews
I have a blood condition and Tylenol is the only fever and pain reducer I can use. Works fast and efficiently! I use it Tylenol anytime I get a fever, have aches and pains or headaches. I can buy Tylenol in grocery stores, big box stores and in gas stations on the go. 
Vanessa C.
Cicero, IL
31 reviews
Extra strength is always the way to go , I do love Tylenol over any other pain relief medication out there. It never fails me when I’m in need , I literally could take it for a headache or leg pain ! It’ll work for eithier or!Tylenol® Extra Strength Caplets for Adults
Mindy M.
Magnolia, AR
23 reviews
My family uses Tylenol for headaches and fever. I do not reach for this first for my sore muscles.  I like that my kids are old enough to swallow these nowadays. I take two and they take 1. I buy at Walmart. They are affordable. I packed a bottle for vacation. 
Rose S.
Massillon, OH
142 reviews
I get really Severe migraines and this has been the only thing that I have found to help with them. I always have this product in my house, car, purse, work. It is a very effective product that I recommend to anyone that gets really bad headaches or just aches in general.
Theresa T.
124 reviews
Wellness Guru Expert Level 1
Tylenol is one of the best pain relievers out there. It is a super reliable medicine. My pain seems to go away instantly whenever I take a pill. The pills are very easy to swallow and are not too big. They're great for relieving headaches, cramps, toothaches, and back pains.
Mindy M.
Magnolia, AR
23 reviews
This tiny bottle is perfect for traveling as well as for my purse. I have a full size bottle that I keep in my medicine cabinet. I use this product for headaches and occasional fever. I buy at walmart. It is affordable. I even use this on my kids ages 10 & 12. 
Nevada G.
Athens, AL
128 reviews
Wellness Guru Expert Level 1
My go to everyday pain reliever has always been Tylenol.  It works quickly and isn't addictive.  It's also inexpensive and works wonders for those minor aches and pains.  In fact, it works better for me than Midol when it comes to that time of the month!
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults