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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Vanessa C.
Cicero, IL
31 reviews
Extra strength is always the way to go , I do love Tylenol over any other pain relief medication out there. It never fails me when I’m in need , I literally could take it for a headache or leg pain ! It’ll work for eithier or!Tylenol® Extra Strength Caplets for Adults
Mindy M.
Magnolia, AR
23 reviews
This tiny bottle is perfect for traveling as well as for my purse. I have a full size bottle that I keep in my medicine cabinet. I use this product for headaches and occasional fever. I buy at walmart. It is affordable. I even use this on my kids ages 10 & 12. 
Courtney H.
Kenesaw, NE
85 reviews
My go to pain reliever. Works pretty well, and works pretty fast. I would recommend this to anyone in pain. Can buy it just about anywhere, which is nice. It is a lot like other pain kills but I think this works a little faster.
Nevada G.
Athens, AL
128 reviews
Wellness Guru Expert Level 1
My go to everyday pain reliever has always been Tylenol.  It works quickly and isn't addictive.  It's also inexpensive and works wonders for those minor aches and pains.  In fact, it works better for me than Midol when it comes to that time of the month!
Johanna V.
205 reviews
Wellness Guru Expert Level 1
For major pain this is the remedy. I had the worst back pain the other day. I took to of these and literally was fine for a few hours. I even too a nap. So worth it. The milagram are kind of high and not my typical but it worked.
Morgan L.
Fargo, ND
19 reviews
I’m not one to turn to pain relievers, I try to work through it. When it comes down to no longer being able to push through I always take these. Does take some time for it to kick in and start working. But that’s the same for everything. Does not work for migraines.
Stephenee M.
Wilsonville, OR
65 reviews
Another go to! This is good stuff that works really well. I again purchase this at Costco for a really big bottle at a super affordable cost! I don’t know if I’ll ever switch!
Sarah E.
Winston Salem, NC
9 reviews
I had the biggest, baddest migraine yesterday and I couldn't get it to go away. I tried absolutely everything to get the pain to go away. Eventually I took a Tylenol and within 20 minutes it was gone for 4 hours. If you get migraines, this is the pain pill for you!
Theresa V.
Tampa, FL
45 reviews
Wellness Guru Expert Level 1
I used to have to use Excedrin Extra Strength when I got a migraine but for some reason it stopped working for me so I started using Tylenol Extra Strength. Whenever I feel as though migraines coming on I take two of these and it goes away.
Christina G.
Bixby, OK
94 reviews
Extra strength Tylenol would help my pain. It’s fairly affordable and can be bought at Walmart. I use it still if I don’t use my migraine prescription. It helps and I will continue to buy and use it for as long as I can. The doc recommended it to me so I use it too
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults