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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Denisse G.
183 reviews
Wellness Guru Expert Level 1
Works great for me and I can take it even if I am breastfeeding so it covers my needs and expectations. I try to always have it at home
Fiona G.
Chicago, IL
132 reviews
For quick temporary relief I stick with Tylenol .I keep this in my purse car and office at work . You never know when you’ll need it .
tammy m.
Strongsville , OH
638 reviews
I sometimes use it and it seems to work they are a little pricey but it is what is it aleve compares pretty good I bought it at walmart
Meaghan L.
Bridgeport, CT
86 reviews
Good for any ache or pain. Definitely a great value! Tylenol is a brand everyone knows and trusts. It is good for a variety of problems
Melissa W.
Rock Hill , SC
31 reviews
I suffer from multiple back issues and Tylenol is always there to help! When I was pregnant with my youngest child it was a life saver!
Hannah H.
Gardendale, AL
48 reviews
Works really well for muscle aches and minor joint pain. Not the best for migraines but it takes care of normal headaches really well!
Lucinda N.
51 reviews
Helps with my headache ant time I need it. Doesn't take forever to kick in. I bought mine from Walmart and it was a pretty fair price.
Denise H.
Jersey City, NJ
118 reviews
Wellness Guru Expert Level 2
This product works, it takes away my aches and pains fast. I have tried taking other pain relievers nothing works for me like this one
Samantha H.
Belfair, WA
61 reviews
I use this for any kind of pain I have. I try not to reach for the meds first but sometimes I just need pain meds and this works well.
Megan S.
114 reviews
Wellness Guru Expert Level 2
I have horrible back pain. For days that are unbearable I’ll take two of these. Really helps me get through the day and relieve my pain
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults