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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Bianca C.
Palmdale, CA
128 reviews
Wellness Guru Expert Level 2
These help so much either if I'm in pain or if I have a headache. Helps with knee pain last a good amount of hours. The price is good.
Jenise W.
Abilene , TX
139 reviews
Wellness Guru Expert Level 2
Works well and gives good pain relief without making you feel drowsy or anything like that. Works well at getting rid of all body pain
Samantha T.
Carrollton, IL
72 reviews
Sometimes it works and others I feel no relief! When it does work, it takes about 20 minutes to kick in but the relief stays for hours!
Stella W.
Revere, MA
73 reviews
This is the only thing I take for my ache and pains! It always does the trick in a limited amount of time! Must have in the house 
Nava S.
Granger, IN
255 reviews
Wellness Guru Expert Level 1
I get migraines often and this medicine usually helps make them lighter. When they don’t go away from this , I take excederin migraine!
Tiara C.
53 reviews
These gets rid of any cramps, headaches or other pains I need to get rid of! It’s long lasting and great because of its extra strength
Mariah F.
Port Wentwrth, GA
47 reviews
I've never had any complications with this medication. Overall they are decently priced. It does take a little while for it to kick in.
Vanessa W.
Eagle Mtn, UT
99 reviews
I love this! Great for horrible headaches and mensural cramps. Takes pain away. And doesn’t give you this jitters other medication does
Denisse G.
183 reviews
Wellness Guru Expert Level 1
Works great for me and I can take it even if I am breastfeeding so it covers my needs and expectations. I try to always have it at home
izma t.
Salem, NH
65 reviews
Helps a lot when I am in any sort of pain or am not feeling well. They come in handy as well at school because they fit right in my bag
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults