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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Anna D.
South Elgin, IL
57 reviews
It's is effective with minor pains and headaches. I always have a bottle in my purse. It is also affordable and accessible at many stores.
Amanda G.
Wheelersburg, OH
165 reviews
Wellness Guru Expert Level 1
Great for simple aches and pains and its affordable. You have to take it more often than I'd like but it works and it's safe while pregnant
Aimee S.
607 reviews
Wellness Guru Expert Level 3
These are awesome! They last the longest in my system and they kick in quick! They are a pretty good value if you shop at the right store.
Jessica D.
Clearfield, PA
22 reviews
Used for years. It's just my go to when I have aches or pains. Usually does the job within the hour. Price is decent for how many you get!
Tiffany H.
50 reviews
Really helps with any pain. It helps when I have a headache, and any kind of body pain. I love how easy it is to swallow & have on the go!
Jenny H.
42 reviews
Great for my headache. I usually try to avoid taking medicine. But it works well, when I have to take it. Good price, great product.  
Kat P.
Minneapolis, MN
258 reviews
I only use Tylenol as a pain reliever for when I am sick as I feel it is a better drug. I take another brand for when I need quick results.
Brandy W.
Kingsport, TN
589 reviews
I use this for a bad headache or mild toothache. For other pains I use ibuprofen. It work great to relieve pain fast and reduces fever too!
Corrine S.
Foxboro , MA
256 reviews
Wellness Guru Expert Level 2
I think Tylenol helps with just about all of my pain! Back pain from working a long shift, headaches, or muscle soreness from over working!
Maria W.
10 reviews
I frequently use this as I get headaches often. Also from when I work out, I get headahes. Tylenol is easy on the stomach and works quick.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults