Woah there, it looks like your browser is out of date.

To get the best experience, please update your browser.

Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Shakyra M.
New London, MO
127 reviews
These are great to pop in your purse to go. This has came in handy multiple of times for not only me but others with me. Definitely stops pain.
Britney B.
Ellicott City, MD
54 reviews
The extra strength tablets help with my intense headaches! I carry these around in my purse all the time, just in case a headache comes around.
Danielle E.
107 reviews
It works sometimes. It depends on the severity of my migraine. When it does work, I have to wait quite a while before it kicks in and helps.
Brii'anna F.
Vauxhall, NJ
26 reviews
It works but it takes a while to kick in . I always use it because it's in the house but it's not bad at all very good for cramps and fever .
Jessyca S.
Colorado Spgs, CO
169 reviews
Wellness Guru Expert Level 1
I find this really effective when I have a headache. Much better than the migraine relief ones, which have caffeine, and make my heart race!
Jennyfer S.
Lawrence, MA
585 reviews
Wellness Guru Expert Level 1
I use these all the time even during pregnancy and it works I thought it didn't buy it does calm the pain in same amount of time as a Motrin
Hailey R.
Sandy, UT
14 reviews
Love the extra strength! My mom has an allergy to almost every pain med but she can have Tylenol. The extra strength is great for migraines!
JoAnn M.
Tulsa, OK
54 reviews
Tylenol is not my favorite brand. It does not work as well as promised, but I like that they sell little vials that are easy to put in purse
Amanda M.
Hillsborough, NJ
49 reviews
Tylenol is definitely my go to medicine for everything. It does it's job and I trust it. Also you can take it on an empty stomach apparently!
Monique B.
102 reviews
Wellness Guru Expert Level 1
I use these when I run out of Excedrine. They work fast but not as fast as other meds I use. If I'm having a migraine I need to take 3 not 2.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

Sign up to join our community!



influenster cashback

Please confirm your email address.

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults