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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Autumn R.
94 reviews
Tylenol is my go to whenever I’m feeling under the weather! Yes it always meets y expectations! Fairly reasonable price and very easy to find! If not taken with food it can really cramp your stomach so beware! I would absolutely recommend it to others especially during cold and flu season!
Liz S.
Katy, TX
206 reviews
Wellness Guru Expert Level 1
I use Tylenol when I get really bad headaches and I can’t seem to get rid of them. I like the fact that they are not drowsy or make me sick. I would pick these over Motrin. Don’t know why but I trust Tylenol more than the other pain meds out there.
Heidi C.
Sparta, TN
217 reviews
Wellness Guru Expert Level 3
Tylenol is my go to for pain. I'm not big on taking medicine so it's few and far between that I make myself take it and I want something that is going to work. Tylenol works for me. It's affordable and it does the job. I will definitely continue taking it for my pain management needs. 
Bianca A.
White Plains, NY
106 reviews
Wellness Guru Expert Level 2
Works great at getting rid of every day aches and pains as well as fever and it doesn’t cause bleeding like other pain relievers do. Would recommend to everyone. It’s a better alternative if you’re on blood thinners or are prone to stomach ulcers
Colleen F.
Raleigh, NC
57 reviews
Effective and usually fast acting, Tylenol is the only OTC pain reliever I use because NSAIDS can cause ulcers, and with stomach issues, I don't want to take a chance.
Alexa S.
Paso Robles, CA
95 reviews
Tylenol is amazing for headaches and hangovers. It quickly rids of the pain and lasts for awhile. I use it whenever I've got a hangover and it works well while also being relatively inexpensive. It works much better than a generic brand, I swear.
Mackenzie D.
South Jordan , UT
90 reviews
Tylenol never hurts my stomach, whether or not I have eaten before taking them. The active ingredient is easier on you than most other pain relievers. It is cheap and effective. I would recommend this to anyone and I always have a bottle on hand.
Denise V.
Salinas, CA
128 reviews
These are a life saver for my cramps and migraines! I carry a small packet with me at all times. I take them and I know they will always work for me. I get mine at Walgreens or the Dollar Tree. They are always stocked. Tried and true thank you Tylenol !
Megan M.
Acworth, GA
12 reviews
Tylenol cures all my headaches after a long day at work or classes. Fast acting and long lasting. It's a great product for anyone as it works for about five hours. I would not trade this medication for anything when I have a splitting headache. 
Jemina H.
Virginia Bch, VA
55 reviews
Gets the job done and always carry a travel bottle in my purse for headaches or minor aches. Can be purchased almost everywhere including gas stations. Compared to most it is effective in a short amount of time and I always recommend to others.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults