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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Cinthya M.
Waco, TX
18 reviews
The only medicine I will ever buy for pain. Any kind of pain. These are literally my go to's. I keep one and home, one at work, and one in my car.
Clara H.
Wenonah, NJ
109 reviews
I do use these with my severe headaches and they do help every time as long as I calm down for a second and I'm not continuously running around.
Racheal A.
Hendersonville, TN
19 reviews
I reach for these when I have a headache​ when my back is killing. My Dr want me to take these over any other ones because of my medical history
Meagan C.
40 reviews
Tylenol has never really helped with headaches. Unfortunately, when it finally starts to kick in it’s like I️ have another headache starting. /:
Stephanie M.
Indianapolis, IN
124 reviews
I could only take Tylenol when I was pregnant as I always had a headache or back pain. Taking these would knock the pain right out. I love these.
ashley c.
Canton, OH
21 reviews
Wellness Guru Expert Level 2
These tylenol seem to work the best for me. They have the longest effect throughout the day compared to other things I have taken for a headache.
Beauty •.
Palos Hills , IL
44 reviews
Tylenol seems to be the only thing that helps me when I get my migraines. This extra strength Tylenol really kicks in fast and gets the job done!
Alex S.
116 reviews
I think its great, it makes the pain melt away pretty fast, its pretty much the only pain reliever I take just because its tried and true for me.
Brande M.
N Las Vegas, NV
44 reviews
Tylenol is our go to product for your general aches and pains, and headache relief. It works the first time you use it, and doesn't let you down.
Taylor M.
Stone Mountain, GA
14 reviews
This is the only pain relief product I like to use. Advil just doesn't cut it for me. I also use this when I have head aches and it always helps.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults