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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
rebbecca L.
Averill Park , NY
93 reviews
The only thing I could take while pregnant/breastfeeding and it did not disappoint! It's one thing I always keep on hand for headaches and colds..
Jessica S.
Little Elm, TX
39 reviews
I like to alternate Tylenol and Advil when I’m sick. Tylenol works but i usually go for Advil because the pills are smaller and easier to swallow.
Brooke N.
67 reviews
I typically do not use tylenol as it does not help my pain as well as other products. It occasionally works for headaches but not much else for me
Abby P.
25 reviews
I have always used Tylenol for every time I have a ache or pain and it helps but be careful how much you take because your body can get used to it
Stefanie S.
193 reviews
I know these have worked before so I have no issue giving this item 5 stars. It would relieve the pain just enough for me to function much easier.
T C.
Ludington, MI
57 reviews
Whenever I have an intensive back pain that leads me to having a horrible head ache, I always go with Tylenol. It’s very effective and affordable.
Fryda M.
44 reviews
It works really fast that's all I could ask for. It's affordable. And I like how the bottle would be hard for kids to open (when it's in a bottle)
Jennifer S.
15 reviews
Great product sometimes I can Cath them on sale 2 bottles for 5$ they got good strong milligrams and I take 4 with in 30min u can tell a difference
Stefanie G.
Kew Garden Hl, NY
93 reviews
My go to for pain reliever. Tylenol always does the job. I am not allowed to take other pain relievers and I never have a problem where I have to. 
Donna M.
Seneca, SC
238 reviews
Wellness Guru Expert Level 1
Pain reliever--it does in fact relieve pain! Tylenol is my preferred pain reliever for adults and children. Affordable, readily available. Win-win
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults