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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
jalie h.
Nicholasville, KY
49 reviews
Tylenol is the only brand we will use in our house it get the job done. No matter if we have fevers or a headache. The off brands don't seem to help.
Domenique W.
Philadelphia, PA
56 reviews
As soon as I feel pain, I take two of these. They relieve the pain right away or help make the pain bearable. It helps with headaches and body pains.
Samreen A.
14 reviews
These have been tne most effective pain killers/fever reducers for me and my family for years. However, in case of fever it does not last upto 8 hrs.
Alexis K.
134 reviews
I am giving this a 3/5. This helps sometimes but then again sometimes it doesn’t. It is affordable. There are many different sizes you can get it in.
Carla S.
Steelville, MO
78 reviews
For myself, I don't like tylenol. It has never helped me. It doesn't relieve my pains or headaches etc. I'd rather use something that actually works.
Erika A.
11 reviews
Tylenol is a must at our home.  It comes in handy for those time in need.  So far its been effective and i will krep buying it as long as they make it. 
Chloe L.
211 reviews
Wellness Guru Expert Level 3
Best product to take for a any pains you may have, I take it religiously and it’s the best out there! I’ve taken this many times and it always helps!
Jesse W.
Salvisa, KY
91 reviews
Wellness Guru Expert Level 2
When I feel a headache coming on, I can take 2 of these and they work almost immediately. I make sure I carry some of these on me at all times. 
Alex P.
Charlestown, IN
20 reviews
Love having this for on the go! I take this along with some ibuprofen to help ease my jaw pain which can happen anywhere! Will always buy my Tylenol
Extra strength is the way to go when reaching for Tylenol. I can't use NSAIDS like ibuprofen or Aleve so this is a great product for pain and fevers.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults