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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Mary J.
68 reviews
I work with toddlers so I am constantly getting sick from baby germs. By the time I get home from work I'm running a 100+ fever. I take two of the tylenol extra strength and it brings my fever back down low or gets rid of it. If I have a fever I would recommend taking two tabs of tylenol extra strength.
Mim H.
piscataway, Nj
108 reviews
Wellness Guru Expert Level 1
Tylenol is the best for when you have a fever, cold or extreme headaches. It’s good value for very affordable prices. I use other alternatives as well, different occasions/scenarios calls for different brands in my case. I’d definitely recommend this to everyone
Jåçkšøñ B.
Stanardsville , VA
110 reviews
I have nerve pain and a lot of times i have to take two of these guys and two naproxen they help some but not much however for head aches and all that i think they work great
Ayishah M.
48 reviews
I have always been an avid Tylonel user! Any sort of pain or sickness, I rely on the same Extra strength Tylonel pills. It works quickly and very good! I would recommend this product to anyone dealing with any sort of pain or illness. Tylenol® Extra Strength Caplets for Adults
harley C.
5 reviews
I had a lot of pain and this products really helped. it eased my pain & made me feel a lot better than i was before. it was a good price for how it worked. it worked like ibuprofen does. i was very satisfied with this product and i will continue using it
Nicole C.
49 reviews
Great for when I have a headache or some other pain. It also works for me when I'm sick with a cold. I think the price is affordable and it meets its expectations. I recommend this product to others. It's also easy to find in stores especially places such as CVS Pharmacy.
Vivian J.
Mc Connellsbg, PA
152 reviews
Wellness Guru Expert Level 2
This product helps With headaches as expected and pain. It is more effective than other products . This met my expectations on how good it would work. I bought this at family dollar store. I am pretty satisfied with this Tylenol and i would recommend it.
Jasmine W.
69 reviews
Wellness Guru Expert Level 3
its very effective, I get relief in under 10 minutes, but it could be different for others. its very highly recommended by me, if you need a good pain reliever. it met all of my expectations and beyond. definitely would buy it again and again and again!
Hailey H.
Paragould, AR
84 reviews
About as great as any OTC medication can be. A little pricey compared to generic brands where you can get the same thing. Does exactly what it should do, though. Overall am satisfied.
Kelsey F.
Summerville, SC
66 reviews
I use Tylenol extra strength for any every day aches & pains as well as menstrual cramps. I find it to be very effective and when necessary will rotate it with ibuprofen.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults