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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Tracie S.
63 reviews
I do take on occasion if I have to pick something up while i'm on the go. They work just fine but I do end up having to take them more than once in a day.
Michaela D.
Phoenix, AZ
150 reviews
Wellness Guru Expert Level 1
Love this for a to go in my purse. I can always buy a big bottle and fill it if it runs low also. It gets rid of my headache in a half hour up to an hour.
Maria V.
66 reviews
Wellness Guru Expert Level 3
I only use Tylenol when I have a normal headache migraine. It's probably the only medicine I use. I don't like taking medication but I trust this product.
Zoey L.
29 reviews
These really help me when I get bad headaches or get hurt at work. They do make me sleepy sometimes but maybe that's just me. Great pain reliever for sure!
Adi D.
61 reviews
These are my jam for a headache, cramps, whatever ails you. I hear they are bad on your lover but my coworker eats them like candy and she's alive so......
FranYiisabel C.
19 reviews
I have always cound on these seens i was prego ao im sure they are good and Tylenol takes the pain away if a pregnant woman can use this it is not harmful
Destyni A.
35 reviews
I love Tylenol for any pain I have. It's so affordable and so worth it. I've bought it from many drugstores and other local stores like target & walmart
Jessica M.
Perkasie, PA
175 reviews
Wellness Guru Expert Level 1
This is my go to pain reliever. I take it when my body hurts or when I am feeling under the weather. I have never had anything but a positive experience.
Ariele K.
Fort Kent, ME
54 reviews
I keep this in my car, in my purse, gym bag it’s always on me all the time to get rid of quic pain when I feel it coming on. It works fast when I need it 
Dori B.
101 reviews
Used because it was pregnant (typically use Advil) but this works just as well in my opinion! I don’t use it often enough to compare it to anything else
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults