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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Taylor G.
Independence, MO
65 reviews
Tylenol sometimes work for me, but sometimes it doesn't. The extra strength has helped with aches and pains, but is not always as effective as other products.
Cassandra S.
Quinby, VA
25 reviews
The only thing to help my headaches and every ache I may have. Large bottle lasts along time. I have used others like a love, ibphrofun that just do not work.
Annie M.
Akron, OH
602 reviews
Wellness Guru Expert Level 2
Pretty good a little expensive, I don't use often only when I have some aches and body pains, but almost always makes me feel better especially when I'm sick.
Lexi a.
180 reviews
These work great for any type of pain. If I have done a very vigorous workout routine I take one of these right after and I don't get as sore. Very effective.
Trina S.
88 reviews
I like using Tylenol extra strength when I have a migraine or body aches (due to fibromyalgia). I lay down for an hour or two and when I wake up I feel better.
Yurgenny G.
Copiague, NY
182 reviews
Wellness Guru Expert Level 2
Estas pastillas aveces no me prueban mucho, si las uso para un dolor de cabeza tarda bastante en hacerme el efecto para que me pueda quitar el dolor de cabeza
Brooklyn G.
Lincoln, AR
68 reviews
These are perfect for any aches and pains you have. I take these for back pain when it acts up. It immediately takes care of it and works for hours and hours.
Marlen M.
Brookhaven, GA
10 reviews
This is a really good item to take it help you alot with head hurting   i   buy it on   CvS also on walmart, QT....one of my friend recomend this and it really workd
Kristin H.
54 reviews
Tyleno is a decent medication. Not one of my favorites but it does the job. It’s a little more expensive for such a small amount. But I will buy if I have to.
Guadalupe L.
246 reviews
Wellness Guru Expert Level 3
This is my go to pain killer. I can always count on it and it never upsets my stomach. I perfect it to others because of the fact it doesn't bother my stomach.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults