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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Shelby C.
Oregon City, OR
140 reviews
Tylenol is one the best pain relievers. When you have any types of pains, it's one of the fastest working relievers there is. I take this and ibuprofen and it works wonders.
Tiffany A.
Shepherdsvlle, KY
63 reviews
This has been my go to pain and headache reliever for years. It does a great job at making my head pains less intense and has never caused any upset stomach issues like some other pain relievers.
Madison M.
Gray, GA
136 reviews
Wellness Guru Expert Level 1
I get bad back and head aches and Tylenol is good for helping both when i don't have a specific type of pain pill. It works pretty well and lasts for a decent time but i wish they lasted longer
Rachel C.
Lancaster, CA
242 reviews
Wellness Guru Expert Level 1
Yes! As someone who suffers from frequent headaches, this is really a life saver! It is fast acting, and does not make me feel nauseous or funny whatsoever. I've been using it for the longest time!!!
Erin Y.
182 reviews
Wellness Guru Expert Level 2
I take these acetaminophen pills whenever I am traveling and always carry a few of the packets in my purse. They help with any kind of headaches or fever or pain that I'm experiencing. 
Julia R.
Crane, TX
96 reviews
Tylenol is great for me. It's very effective. I have a sensitive stomach. I love that I can take this on days that I don't feel like I can eat. It doesn't make me sick. I recommend to everyone
Zaira A.
72 reviews
These pills are effective but for only a certain amount of hours and than the pains just comes back. I don't really personally like taking pills myself but these help a bit but they're not the best
Cheyenne C.
12 reviews
Typically when I have a headache I head to my bathroom and take a couple of these bad boys. Soon after my headache will disappear. It seems to help most days where other pain relievers do not.
Kristen S.
86 reviews
Tylenol was my go to pain pill for when I have surgery because it doesn't thin my blood (which would make me bleed more) and it does the job of taking away pain. It's affordable and I love it
Ashley R.
Holland, MI
42 reviews
I know it's weird, but I like the taste of these. (Not that I EAT them, you know what I mean.) they don't taste medicinal on my tongue when I need to take some. Only thing I use for headaches.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults