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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Tiffany W.
Gray, TN
89 reviews
Wellness Guru Expert Level 2
Tylenol is amazing for pains either by itself or added to something else. If I have a headache I take 1 of these and 1 Excedrin instead of the 2 Excedrin because it makes me jumpy. the combination of the 2 works well for me
Melissa W.
Crown Point, IN
50 reviews
Tylenol Extra Strength caplets seem to be effective, whether I need them for a headache, backache, or other pain. Just about every time I need to purchase Tylenol, it is on sale. I usually purchase it from Walgreens or CVS.
Blanca V.
Phoenix, AZ
61 reviews
Tylenol is always the second medicine that I grab for if nothing else is available. I buy it at Walmart Or sometimes the dollar store. Use it mostly for headaches. Tylenol® Extra Strength Caplets for Adults
Ashley F.
Lawrenceville, GA
43 reviews
Wellness Guru Expert Level 1
My go-to for everything pain related- headaches, menstrual cramps, hangovers, etc. etc... It's super affordable too! Everyone should have a bottle of Tylenol in their home!!!
Saher J.
Aldie, VA
125 reviews
Usually my go to pain reliever during that time of the month or any aches or pains I may get randomly. It takes about 20 minutes to work so I usually take it and take a nap if the pains too much and wake up feeling fresh.
nolan s.
Corona, CA
89 reviews
helps my eye straining migraines, i bought a larger pack at sams club when i was in volleyball bc i'd get dehydrated so i would have to drink a lot of water then take one of these. my headaches were gone and left me satisfied
Payton C.
5 reviews
I would definitely recommend this product. I am not able to take other pain relievers due to other medications i am currently on. I tried this and it definitely works and lasts quite a while compared to others i’ve tried.
jaimie l.
68 reviews
Just my simple go to medication for all around everything. I especially use this when I have cramps or a major headache. I try my best to not take medication but if I really cant handle it then I take tyenol. It has worked very well for me all of these years and I would gladly continue to repurchase. 
Chantae C.
Salinas, CA
114 reviews
Wellness Guru Expert Level 1
I suffer from migraines honestly nothing works better for them than tylenol...i always carry a little bottle with me for my headaches and although it takes about 15 to kick in...it really takes my headaches away and doesnt take long!!
Jacey B.
Bowling Green , KY
79 reviews
Tylenol is my go to, to kick pain away! I only use it as needed not on a day to day basis. It is very affordable and works great!! I buy it at Walmart or Target. I'll definitely buy it again and always use it when needed!
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults