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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Chelsey B.
Milledgeville, GA
781 reviews
Wellness Guru Expert Level 2
This is a no brainer to keep in your medicine cabinet. Between injuries, aches and pains, and fevers. It really does it all. It works for four hours and takes the edge off. I always keep this on hand just in case.
Alexa H.
Richmond, IN
156 reviews
Wellness Guru Expert Level 1
I get really bad migraines, and while these won't help with that pain, they do help when I get a minor headache. They also help with any other mild aches or pains.
Kimberly S.
Copperopolis , CA
18 reviews
Tylenol is much milder on my body than ibuprofen. I've been following the Autoimmune Protocol & ibuprofen is on the restricted list, so I've rediscovered that Tylenol is a great alternative for any aches or pains.
Ash C.
145 reviews
I always reach for Tylenol when I have pain or a headache. It gets the job done. I usually buy it in bulk at SAMs Club because it's great to have around the house.
23 reviews
It helps me a lot to relieve my headaches and I always keep it with me in my purse. I've learned to take my Tylenol as soon as I feel the pain starting them I can control easily the level of pain and discomfort.
Terry g.
Fort Riley, KS
124 reviews
who doesnt have Tylenol as a go to for minor pain relief or fevers.it gets the job done even though sometimes you wished it worked faster but over all I love it.
Jessica E.
33 reviews
These are great for travel and or to carry in your purse. You never know when a headache will strike so you have to be prepared with some Tylenol extra strength.
Christal T.
17 reviews
These are great on the go!! I keep one in my car and one in my purse. It's so much easier to travel with this size than to carry around a bottle with 100+ pills.
I only use this product when I'm in any type of pain. I always buy over the counter. Very much affordable only will cost u a couple dollars. I use it the most so I really don't know how other pain relievers are.
Randi B.
3 reviews
Tylenol is my go to for aches , pains , and headaches. I typically don't like using medicine but this works quick and doesn't make my stomach sick from using it.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults