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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Afnan A.
Tallahassee, FL
126 reviews
Really helps with any kind of pain it's so great like if my back hurts I take some and it helps same with headaches and everything along those lines. Highly recommend
Jane P.
Columbia , SC
112 reviews
I always take this when I'm sick. Nothing else breaks a fever like Tylenol does! Also a great pain reliever. Better than Advil for that but doesn't help inflammation
Megan A.
Dickens, TX
236 reviews
Wellness Guru Expert Level 1
This is perfect for on the go. I have one in every onr of my purses and i leave it in my car too! I like how accesible it is without having to carry the bigger bottle.
Kymberly E.
Springfield, IL
49 reviews
I used to love Tylenol ( it works great) but a few years back they had a major recall. I had 6 total bottles of Tylenol. 2 infant ones, one at daycare and one for home. 2 children's tylenols, also one at daycare and one at home, 1tylenol arthritis, and 1 Tylenol extra. During the recall we were told to call in with the numbers off the bottles. We'll I did that and all I got back from them was 2 $3 off coupons good for more Tylenol - which I couldn't even buy for the next year. I now refuse to buy any Tylenol products because a company that will not even replace or completely reimburse a customer when they have a mandatory recall is a crap company!!
Ashley S.
Coral Springs, FL
170 reviews
Wellness Guru Expert Level 1
I would say Tylenol is in my top pick for pain relieving medication. The pills are not as easy to swallow as some other brands, but they do take effect quite quickly!
Rebecca M.
142 reviews
This always has to be stocked in my home. I have a little bottle also in my purse. I suffer from migraines and aches and pains occasionally and it gets her job done.
Jessen K.
18 reviews
Works well when I have something that is aching or a killer headache. Usually I don't like to take anything but this is my go to when I can't stand the pain anymore.
Katie C.
Lyford, TX
21 reviews
Love extra strength Tylenol when I need a little pain relief. Usually helps pretty well. Depending on the pain level seems to work pretty well. Price is to be expected and is not much more than other leading brands.
jessica f.
22 reviews
Helps with my daily pain. I use the extra strength because it works quickly. I take it when I get migraines from my allergies and it has really helped keep me going
jayde m.
Bradford, OH
34 reviews
Definitely helps with soreness and achyness and so does the arthritis kind. Decently priced and we all know that expectations can't be completely met but worked well enough for me and I am satisfied with the results
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults