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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Mary D.
Marion, NC
61 reviews
I have found that when I have a headache, Tylenol Extra Strength is more effective than anything else that I have tried.  I don't like taking medicine if I can help it, so I only take it when I need it. I always have this product at home & in my purse. 
Cherise M.
27 reviews
Since I had my son I can't take anything other than tylenol because im breast feeding. This for me doesn't do the job. I have to take 4 and drink coffee. Just to take the edge off.
Jessica M.
Hudson, Nh
58 reviews
Tylenol is my go to pain reliever for headaches. I don't like taking pills and try to tough it out when I can but I trust Tylenol the most for the occasional time I need pain relief
Meg S.
Orlando, FL
86 reviews
I had a stomach surgery that prevents me from taking NSAIDs, so Tylenol is my go-to for pain control. It works well for combating headaches, fevers and menstrual cramps. I love it!
Portia T.
Ionia, MI
110 reviews
Wellness Guru Expert Level 2
This is my go to pain reliever medication. It helps with cramps, headaches, back pain, and more. I can take it while breastfeeding without being worried. I would highly recommend this product.
Chastity J.
Abilene, TX
211 reviews
Wellness Guru Expert Level 2
It works good on fever or muscle pain. I like the travel size of this product. It fits so easy in my purse. I don't really like caplets but they are effective. I would purchase again.
Amelia P.
Blowing Rock, NC
48 reviews
Advil and ibuprofen really irritate my stomach especially when I don't eat much with the medication. Tylenol really does not irritate my stomach and actually works to relieve pain!
Zally R.
Bronx , NY
126 reviews
Wellness Guru Expert Level 1
Well Tylenol is my #1 for every type of pain I get , for those who are allergic to NSAID like I am , this is the best thing we can drink for all types of pain but believe it or not it would take pain away if you drink about 3 lol but so worth it
Erin D.
Penn hills, PA
378 reviews
These guys are a mainstay in my medicine cabinet. Take two for any pain or a fever and you will feel better in 20 mins or so. Plus they help with inflammation and are easy to swallow
Lily L.
Houston, TX
180 reviews
These are great pills. I think they work as well as Advil. I like them because they are an alternate pill if you don't want to get Advil. I think it is effective.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults