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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Christin C.
58 reviews
I take these whenever I've been having a headache for hours. It helps relieve the pain and I really recommend this. Compared to alternatives, it does it's job super well. I am always repurchasing.
angelica r.
victorville, CA
23 reviews
Takes away my pain. Can find in most big retailers, 99 cent store, dollar tree, gas stations. Although it works the same as other generic brands I always lean towards this one. Works well.
Matthew W.
N Las Vegas, NV
63 reviews
I love these for when I have a very strong headache or stronger pain. They relieve it better than other brands I've tried. Pills are small and easy to swallow. I would buy again and I always do!
Amber W.
S Salt Lake, UT
319 reviews
I'm allergic to ibuprofen so I always have this on hand. It is great for fevers and minor aches and pains. Usually go for generic brands because of the price difference but you can't go wrong either way
Maite A.
Miami, FL
32 reviews
These are my go to when i have any type of ache since im breastfeeding my son. They are good but they dont work much when i have a migraine. It sometimes aleviates the pain but by the third dose.
Rossana H.
Anderson, SC
107 reviews
You can always count on relief! Great quality and very effective. You can buy it pretty much anywhere I usually buy it at Walmart. Would consider it the best compared to the alternatives in the market!
Hadia |.
Smyrna , GA
30 reviews
I get frequent headaches and body aches due to scoliosis and this really helps ease the pain all over my body. Definitely meets expectations. I use it a few times a month and I'm satisfied with it. Would recommend.
Sierra K.
Newport News, VA
73 reviews
I don't love Tylenol as much as I like Advil, but I will take Tylenol if there is nothing else. I feel like Tylenol takes too long to kick in and doesn't do the job as well as ibuprofen or Advil
Vanessa F.
San Jacinto, CA
154 reviews
Wellness Guru Expert Level 1
You can never go wrong with Tylenol extra strength. It usually kicks in about 15 mins after you tKe it, that can vary. I take it every time I get a headache or when it's that time of the month. It is the only pain reliever brand I use.
Samantha D.
Grants pass, OR
26 reviews
I usually take this wh we n I'm sick it helps me sleep. It works really good. And it doesn't take to long to kick in. I usually buy it at a Wal-Mart or a store like that.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults