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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Vanessa E.
294 reviews
Wellness Guru Expert Level 3
This were my life saver when i was pregnate this is the only thing i could ever take so they are good and also pregnancy friendly but remember its better not to drink medicine when pregnant
Kayla S.
21 reviews
I'm pregnant so I'm limited as to what I can take. When I suffered a recent sunburn, this extra strength Tylenol was exactly what I needed (as well as lidocaine-aloe). Definitely recommend!
Melissa B.
Turtle Creek, PA
48 reviews
It works great. If i have a headache and any minor pain i take tylenol and boom headache or pain is gone. If i take it right when i feel a migraine coming on i dont end up having a migraine
Terra J.
Xenia , OH
1329 reviews
Wellness Guru Expert Level 1
I’m unable to take a lot of medication due to it making me sick to my stomach.. but Tylenol has always been the one thing to kick my migraine when it comes! It works better than most things I’ve tried.
Taylor A.
Carencro, LA
44 reviews
Wellness Guru Expert Level 1
Tylenol works great for headaches and minor pain relief. This product always meets my expectations. Very effective for helping minor aches and pains and I love that you can purchase at any drugstore or pharmacy
Shannon C.
Charlotte, NC
62 reviews
Wellness Guru Expert Level 1
I cannot use NSAIDS due to stomach surgery. Therefore, I rely on acetaminophen. Tylenol extra strength helps with headaches, body pains and fevers in a timely manner. I definitely recommend it.
Rosalyn D.
Glide, OR
5 reviews
These are great for managing my pain. They are easy to swallow. I am reaching for a pain relief 2 to three times a week being a cna at the hospital your back and knees can hurt from time to time these are great and I recommend them to everyone and my coworkers 
Valerie Z.
San Benito, TX
197 reviews
Wellness Guru Expert Level 3
Easy to take and easily fits into any purse or little pouch. I usually take two pills to make sure it keeps me pain free all day. For a descent size bottle it's affordable and works good.
Raven M.
62 reviews
Make sure to take these bad boys after a night of drinking. (If you are 21+ or of legal drinking age in your country). Super affordable and portable. Helps so much with head aches and cramping.
Desiray S.
Fort Thomas , KY
418 reviews
Wellness Guru Expert Level 1
Tylenol is not my go to pain reliever... it just isn't. But while I was pregnant these were my life saver. I couldn't have made in through those nine months with out them. I am truly thankful.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults