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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Amanda M.
Bridgeport, CT
156 reviews
Wellness Guru Expert Level 1
This is great for any aches, pains, or headaches I get, especially when associated with my period. Super helpful and not too expensive. Also easy to find as it is found in most stores near me. I recommend it.
Winifer A.
New Bedford, MA
29 reviews
Definitely don't have anything bad to say about these multi packs of medicine. They work absolutely great for a small to medium size work place where you don't want everyone digging into a single bottle of pills. They also make it easy to keep track of stock and when you need to reorder.
Jocelyn M.
Kingston, PA
48 reviews
I always keep Tylenol extra strength in my house. I use it whenever I have bad cramps. It works so quick. It's easy to get a single pack from the corner stores. &it's not pricey at all
Darlyn N.
Jackson Hts, NY
209 reviews
Very effective for any pain reliever Tylenol® Extra Strength Caplets for Adults
Good price too i buy the small bottle
Beter if it i take the tylenol pm
Yea would keep buying everytime i need it
madison 💖.
Newark, DE
145 reviews
When I was pregnant the only pain reliever I could use was Tylenol and it did not work at all. I don’t like using medicine but if I’m in a lot of pain I will. Taking this was basically just putting medicine in my body with no help for my pain. Would not recommend and never using again.
Audrey C.
17 reviews
I normally do not take any medications what so ever. But I find I am always reaching for Tylenol Extra Strength because it has always seemed to work for me quickly. I highly recommend.
Kayla B.
150 reviews
It’s okay I guess it gets the job done. Doesn’t make me feel sick or anything. It doesn’t upset my stomach either like some other medication. Yes I would buy again. Yes I would recommend.
Emma C.
14 reviews
Tylonal is really good for pain relief. I use it when I get headaches all the time. The value is great! It definitely works great for headaches. I always bring tylonal with me. Some people use Motrin, because they find it better for pain relief, but in my opinion tylonal works faster. 
Courtney N.
27 reviews
I love tylenol. I can't use ibprophen, so this is the next best thing. It is affordable and located at all local pharmacies and grocery stores. It takes the pain and aches away in a  matter of 30 minutes. It is worth it for a back pain or for a serious head ache i would buy again
Natalie L.
233 reviews
Wellness Guru Expert Level 2
Either a staple in my household, and we cannot live without a bottle of Tylenol around. They’re on the smaller side and easy to swallow, and don’t leave a strong  taste in the mouth. Tylenol is easy to find, as most grocery stores carry it. It’s a great pain reliever and fever reducer.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults