Woah there, it looks like your browser is out of date.

To get the best experience, please update your browser.

Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Graydon W.
maple grove
4 reviews
Just about anytime I have a headache or anything I will check to see if I have Tylenol first. Works fast and don’t have to take extras. What is said on the bottle is how much intake and it works every time
Shawnessey A.
North Grafton, MA
40 reviews
I can't take Advil so Tylenol is always there for me when I'm in pain at all. It's also nice that it can make you a little drowsy so I can take it when I'm in pain at night and it will help me sleep faster
Gleisi G.
Twentynin Plm, CA
111 reviews
Whenever I get a headache or my body hurts for whatever reason my house is always stocked with Tylenol. It’s what I am comfortable with. I can always rely on this extra strength to get me through the day!!
Chelsey M.
Shoreline , WA
35 reviews
Wellness Guru Expert Level 2
Safe while you're pregnant and get those terrible headaches :/ I usually use ibuprofen but can't, so I've switched to this when I need it and it does the job. Not really much else to say, I'd buy it again.
Maddy M.
31 reviews
I recently had a tooth infection which gave me the worst pain of my life. I lived on these for about a week and these were the only pills that could relieve me of my pain. 
Eva R.
Columbus, OH
43 reviews
About the only thing I use when my head is hurting they work really fast and work all day I have about 3 bottles on hand one in my car one in my bathroom and one in my diaper bag
Bella I.
34 reviews
I suffer from reflux and can only use Tylenol (not Advil or Alieve). It works for minor headaches and minor aches and pain. I have a high tolerance for medication so I often feel I need something stronger.
Maria V.
30 reviews
Tylenol to me is the best pain relieving medicine. Granted I think that everyone has different tolerance and medicine that works for them but for me this stuff is the best for aches, pains, and headaches.
Vic B.
Staten Island, NY
37 reviews
Helps relieve your pain and works really quick! Can find this item in a variety of stores for a good price. They have multiple different strengths, depends on how bad you need it. Love this, it works great
Briley T.
60 reviews
The packaging makes traveling much easier than a big bottle. The size of the pill is great and easy to swallow. You feel relief pretty quick and it is well priced. I will definitely buy this product again.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

Sign up to join our community!



influenster cashback

Please confirm your email address.

6 characters minimum. Password must consist of letters, at least 1 number and 1 special character.

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults