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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Derin K.
8 reviews
Tylenol is a product that I have used since I was little and it is a very good headache and fever reducer. I take two tablets and feel fine in a matter of an hour. It is very fast to kick in and very effective.
jazmin T.
Portland, OR
33 reviews
Tylenol has become a household name because they're good a what they do. This product is a good pain reliever and is works pretty fast. Whenever I don't use ibuprofen, I pop one of these for my menstrual cramps.
Anjanette A.
Fort Worth
6 reviews
I have major shoulder pain and get frequent headaches, I’m not one who likes to take pain medicine because they usually don’t work. However these always, always relieve the tension and allow me to enjoy my days.
Melisa T.
Pembroke Pnes, FL
118 reviews
Tylenol extra strength works fast on any pain. It’s about the same as other pain relievers. I bought this at cvs pharmacy. It’s extremely effective, not disappointing at all. I absolutely recommend this to everyone.
Kayla Y.
Bowie, MD
73 reviews
I like this when there isn’t any Advil and these are better for breaking fevers. But they don’t last long and work as good but the get the job done when you don’t have anything Advil
Memarie G.
['The Woodlands', 'TX'], TX
6 reviews
This extra strength Tylenol takes away the pain wether my head is pounding or I'm sore from the gym! Some people have problems taking pills but these are the smallest and easiest pills to take when your in pain!
Mai N.
25 reviews
I like to take Tylenol best when it comes to relieving pain. To me, it seems to work the best and gets the job done. I usually don't take pain medications on a regular basis but when I do, this is my best friend.
Abby G.
217 reviews
Wellness Guru Expert Level 2
Tylenol ES is always my go to pain reliever first. It works so well! I only ever have to take like 2 and my pain goes away. It's not expensive either. I'd recommend to everyone! I always carry a small bottle in my purse.
Kristy H.
Miami, FL
146 reviews
Wellness Guru Expert Level 1
Tylenol is a trusted brand for many years and it works . Two pills and your pain goes away. I always have Tylenol at home for me and the hubby. It works just as good as any alternative. Great buy and inexpensive.
Brittany J.
142 reviews
The Tylenol extra strength capsules are great to have in you’re household or on your person if you need pain relief. It starts working in 30 minutes and reduces any pain that I have had when using this product.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults