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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #43 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Emily D.
Wilton Manors, FL
39 reviews
Wellness Guru Expert Level 1
Super helpful for when you're out and need a pain reliever! Compact, affordable, and you're not left with a bunch of extra tablets you don't need. I usually pick these up when I'm traveling and keep them in my bag just in case
Sami N.
Las Vegas, NV
561 reviews
Wellness Guru Expert Level 3
The only pain reliever that works for me. I can feel it kick in right away which is so needed! It works fast and it works very well. Especially while being pregnant it's such a life savor when I'm truly in need !
Alexandria D.
Oxford, MS
31 reviews
I have aches and pains quite often with knee problems and this is my go to for pain. This also helps with my headaches or menstrual cramps. It is very effective and I would definitely buy it again in the future!
Margaret D.
San Diego, CA
37 reviews
I tore my ACL about 5 years ago and every now and then when the weather changes its starts to ache! Tylenol really cleans up the pain fast and efficiently, making me forget about the old injury. Very satisfied.
Torie H.
143 reviews
I carry Tylenol in my purse all the time. This is a product our family uses for everyday pain relief as needed. I would suggest this product to others as an effective pain relief medication. It is not to strong
Amber C.
Montgomery, AL
66 reviews
Always works if I'm having pretty much any body pain usually kicks in within the hour and I'm good to go. I don't feel like it makes me drowsy and not able to do what I need to but just numbs the pain I'm having
BreAna B.
Waco, TX
164 reviews
Love tyleol! it was the only thing that saved me from pains when I was pregnant and it helped me tons after I had my kids. This stuff works great, highly recommend!
Leslie C.
90 reviews
Wellness Guru Expert Level 1
I honestly don't take pain pills other than for menstrual cramps. These work very well for that type of pain. I've also used these in the past for fever and work good as well. They are found at any drug store really :)
Jayde N.
23 reviews
Decongested my sinus efficiently, and therefore helped me get through my exam period without annoying everyone with my running nose and sniffles! Also slightly soothed my sore throat, reducing how much I coughed.
Ryley M.
22 reviews
The best thing I have taken for pain. It works very well. I have yet to be disappointed. It is about equal to its competitors depending on what you need it for. It's a great price. I buy it as soon as I run out.
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults