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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #38 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,413 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5413)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Alane E.
13 reviews
For years every month I would suffer to the point I had to take two different prescription pain meds every month. Ever since I had my kids I notice that this is now the only product that works for me. 
Jessica S.
Colesburg, IA
60 reviews
Tylenol is what I use for muscle and joint pain. I love this stuff. Extra strength because it works longer and more effective and kicks in pretty quickly. Easy to find. Price is great. Can’t complain
Kay G.
Apache Junction
11 reviews
This is a live sacer.i honestly wouldnt be able to survive without this. I get major migranes.and i twisted my ankle about two weeks ago so these save my life during volleyball and basketball pratice
Alex P.
Tempe, AZ
27 reviews
I don't like taking pain medications, but the tooth ache and headache from my wisdom teeth coming in was driving me to tears! Picked up a bottle and only took one 500 mg pill and I felt relief that lasted throughout the entire day!
Chelsea C.
Denton, TX
57 reviews
I keep these in my car for those sudden back aches from carrying around toddler and a newborn. Compared to other pain relievers this work the fastest and longest for me. I will continuing buying these and would recommend to others.
Estefany N.
johnson city
250 reviews
Wellness Guru Expert Level 3
These are always in my backpack. I have one in my medicine drawer and another travel size one. I can get headaches sometimes and this is always saving me. Best for my pain.
Whitney P.
Lk Havasu Cty, AZ
59 reviews
These are helpful while I am breastfeeding or pregnant and get a migraine. I love knowing Tylenol is a trusted brand by my physician and that I'm not harming my baby in any way by taking it. I wish there was a rapid release version
Yasmine A.
Bloomington , CA
32 reviews
Wellness Guru Expert Level 1
This is basically what I go to if I ran out of my other pain killer.It's good but I find myself taking more than two  and sometimes the pain doesn't even go away cant really depend it this brand but still good as a back up!
Kachi N.
172 reviews
Wellness Guru Expert Level 1
I use this all the time for my menstrual cramps and it always meets my exceptions of soothing the pain. It’s very affordable it’s better than alternatives I recommend this to everyone for pain relief
Katie M.
Conway, SC
56 reviews
Would recommend this. It’s my go to at work whenever I have a head ache for pain. Good value and can be found at most places( Walmart target or pharmacy’s) Tylenol is just always my go to. Works fast
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults