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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Elise S.
Mercedita, UT
18 reviews
I don't go anywhere without this in my purse! It helps SO much for anything from a headache to a stomach ache to overall muscle pain. It is very effective and safe to use, I don't have to worry! Plus you can just pick it up at any local grocery store. I recommend  Tylenol® Extra Strength Caplets for Adults to everyone!
zakkiyah p.
114 reviews
Wellness Guru Expert Level 1
This is great for me when im in pain. Since im allergic to ibuprofen/ aspirin i use this cuz one it keeps me safe and alive. And two because it works for me abd doesn't make me feel like im high off a drugs.
Abbey C.
Rush City, MN
176 reviews
When you have a headache, Tylenol is the way to go. This is a great brand of acetaminophen, and is a great alternative to generics. Available practically anywhere. I am definitely satisfied with this product.
Shannon P.
140 reviews
This is great when I need to kick a migraine to the curb fast. I have this at work and home and it provides quick relief when needed. You can typically score this on a sale at CVS- highly recommended.
Vanessa O.
21 reviews
These are by far the best pain pills like seriously these pills stopped a rotten toothache that I didn’t even know I had making these the only pain relievers I use overall very satisfied with these.
Casey J.
64 reviews
Tylenol is perfect for many aches and pains. I use them for headaches, neck pain, back aches. I keep Tylenol on me at all times, because you never know when you need it. Tylenol is a trusted brand.
Sophia V.
Houston, TX
153 reviews
This is an excellent medication and it does not require a prescription from a doctor; however, I would recommend consulting a physician before using 500 MG tablets on a regular basis. have it at home and a little bottle on my purse. I recommend this product 100% to be used for any minor pain, fever so for arthritis and joint pain.
Marcie M.
Davison , MI
1192 reviews
Wellness Guru Expert Level 2
Works like a charm. This is very effective for my headaches and neck pains. I like how it works on pain without me feeling groggy or dopey. It is very fast acting, and a great deal for your money.
Yuko S.
Anaheim, CA
64 reviews
Whether I have a headache or period cramp, tylenol has helped me relieve of aches very often. I get massive cramps sometimes and taking just one or two dosages of tylenol helps me get through the day.
Michelle N.
Bronx, NY
469 reviews
Honestly I hate taking pills but I’m never afraid to take a Tylenol when I’m experiencing migraines or even a little back ache . Affordable and does the job very well . Definitely I’d buy again .
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults