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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Sabrina B.
Dearborn Hts, MI
170 reviews
The best medicine for any ailments, aches, headaches, muscle aches or sicknesses. It kicks in so fast and its effects are quite long lasting as well. This has become one of the only medicines I use when I feel quite ill or under the weather
Simonna K.
Beverly Hills, CA
46 reviews
Easily the best over the counter product to help numb moderate level pains when needed. It pretty much meets all my expectations and never fails to disappoint me when I do decide to use it! Whenever a friend has pain, I recommend it to them!
Kristen C.
Broken Arrow, OK
104 reviews
These work when you need them to they kick the pain out where you needed to iPod these at Walmart they are very effective not disappointing and that exceeded my expectations I am very satisfied with this product's
leanna b.
Wheelersburg, OH
173 reviews
Wellness Guru Expert Level 1
I use tylonal daily because I get headaches every morning. I wake up with a headache and have to use tylonal and ubrephrwn. My mom just bought me two packs today she dropped them off on her way to work. I would recomend them for headaches
Afshin A.
Brooklyn, NY
86 reviews
Wellness Guru Expert Level 1
I use Tylenol for all kinds of pains. I have ulcerative colitis. My doctor recommend only Tylenol because of my condition. I also have arthritis and Tylenol helps me do all my house works more effectively
Daiane M.
Atlanta, GA
14 reviews
From someone who has migraines at least once a month, it's always good to carry these in your purse!
It's always effective and much better than the regular pills.
Would definitely recommend and buy again!
Mistie M.
32 reviews
Definitely a relief when I was pregnant! This was the only pain medicine that I could take. It met my expectations and was very effective. I would recommend to anyone whose pregnant. I am overall satisfied
Lindsey Z.
Pittsburgh, PA
531 reviews
Wellness Guru Expert Level 3
These are always nice to grab at a gas station or on the go when I’ve got a headache or am in a hurry. Obviously it works just as well as the full sized ones and they are priced about the same as all others.
Becca t.
Port Hadlock, WA
62 reviews
Wellness Guru Expert Level 2
All ladies should have this in there purse. You never know when that headache will pop up. I get asked almost everyday if I have any Tylenol. Yep because I might need it. Be responsible use child safe caps & teach little ones about medicine.
Kristal R.
El paso, TX
360 reviews
Wellness Guru Expert Level 1
Tylenol extra strength works really good!! I love to drink them when I have really seeing headaches.. it literally works within minutes! If you're a person who gets really bad migraines like I do, this is perfect for you, I definitely think you will love them!
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults