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Tylenol® Extra Strength Caplets for Adults

BY TYLENOL #42 in Pain Relief

4.5 out of 5 stars
  • 5 Stars67%
  • 4 Stars25%
  • 3 Stars6%
  • 2 Stars1%
  • 1 Star1%
4.56 / 5 based on 5,417 Reviews


Get back to the things you love with powerful relief of tension headaches, back pain and more.

Available as caplets. For adults and children 12 years and older.

Active ingredient

Acetaminophen 500 mg (in each caplet)


Pain reliever/fever reducer

Inactive ingredients

carnauba wax*, corn starch*, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate, modified starch*, polyethylene glycol*, powdered cellulose, pregelatinized starch, propylene glycol, shellac, sodium starch glycolate, titanium dioxide
contains one or more of these ingredients


carnauba wax, crospovidone, FD&C red no. 40 aluminum lake, hypromellose, magnesium stearate,  microcrystalline cellulose, polyethylene glycol, polysorbate 80,  povidone, pregelatinized starch,  propylene glycol, shellac glaze, sodium starch glycolate, stearic acid, titanium dioxide.


  • temporarily relieves minor aches and pains due to:
  • the common cold
  • headache
  • backache
  • minor pain of arthritis
  • toothache
  • muscular aches
  • premenstrual and menstrual cramps
  • temporarily reduces fever


Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are allergic to acetaminophen or any of the inactive ingredients in this product

Ask a doctor before use if you have liver disease

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

Stop use and ask a doctor if

  • pain gets worse or lasts more than 10 days
  • fever gets worse or lasts more than 3 days
  • new symptoms occur
  • redness or swelling is present

These could be signs of a serious condition.

If pregnant or breast-feeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222) Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.


  • do not take more than directed (see overdose warning)

adults and children 12 years and over

  • take 2 caplets every 6 hours while symptoms last
  • do not take more than 6 caplets in 24 hours, unless directed by a doctor
  • do not take for more than 10 days unless directed by a doctor

children under 12 years

ask a doctor

see more...

Top Questions See all 4 Q&A

Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults
Reviews (5417)
Q&A (2)
Media (38)
  • "I get headaches more than I'd like to, so I just take one and I will start to feel better after a bit." in 1 review
Nordy R.
providence , RI
67 reviews
Idk what's in the pills but it works some time so have really bad headaches n this product saves the day is Also great for back pains and fevers it calms me down without making em sleepy which is my main thing cus I have a child to take care off
Nichole S.
Houston, TX
129 reviews
I find that aspirin and Tylenol products do not work as well as ibuprofen products for me as it relates to pain. I find I have to take more than one dose at times in order to get some noticeable pain relief.
Bianca M.
Roslyn Hts, NY
186 reviews
Wellness Guru Expert Level 2
I sometimes go for these when I have a bad migraine. It can be found anywhere and is affordable. It's disappointing because it isn't always effective for me, but it all depends on the severity of my migraine at the time. All around, good pain reliever.
Lauren K.
Cincinnati , OH
207 reviews
Wellness Guru Expert Level 1
I always take these when I have a headache. I have a hard time finding a pain reliever that will effectively eliminate or soften my headache. I always purchase these at Kroger.
Lillian G.
Edinburg, TX
109 reviews
Pretty good at time. Sometimes it doesn't do much. My only go to product for pain that I can't handle. Although it doesn't kick in as fast as I would like it to but it does justice. Constantly repurchasing.
Bridget O.
Long beach, CA
5 reviews
Tylenol just speaks for itself . It’s always my go to pain reliever . It always helps with whatever pain I’m having whether it’s headaches , stomach aches and it does wonders when you have fevers . I definitely recommend giving Tylenol a try .
cynthia m.
new york, NY
62 reviews
Wellness Guru Expert Level 1
usually when i run out of ibuprofen i always get tylenol extra strength because it does in deed work for me...it gives me no issues and relieves my pains in a short amount of time specially when i get my usual back pains..thank u tylenol for this product 
Mackenzie P.
49 reviews
Tylenol is a great pain reliever and the extra strength ones go above and beyond repairing your aches and pain. Although the pill size is above average, I don't mind at all! The outcome is amazing, you'll feel as good as new in a few minutes.
Danika L.
132 reviews
Wellness Guru Expert Level 1
I mean, tylenol works. I feel like most people know that. I like to rotate between acetaminophen and ibuprofen for the sake of my body. Because of that I keep tylenol around all the time. Good for aches and pains and headaches. Very effective. 
Kimberly L.
El Monte, CA
189 reviews
These are my favorite pain relievers because I can take them on an empty stomach without feeling nauseous afterward. They aren't too difficult to swallow and are very accessible as they are sold at mostly an pharmacy or drugstore that I've been to
Leidy daliza R.
Doral, FL
208 reviews
Wellness Guru Expert Level 1
Do you like this product??
Amber M.
Zanesville, OH
1275 reviews
Wellness Guru Expert Level 4

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Tylenol® Extra Strength Caplets for Adults
Tylenol® Extra Strength Caplets for Adults