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Tylenol® Cold + Flu Severe Day & Night Caplets

Tylenol® Cold + Flu Severe Day & Night Caplets

BY TYLENOL #41 in Cough, Cold, & Flu

4.4 out of 5 stars
  • 5 Stars67%
  • 4 Stars23%
  • 3 Stars4%
  • 2 Stars5%
  • 1 Star1%
4.49 / 5 based on 78 Reviews

Product Description

Convenient caplets to relieve painful cold and flu symptoms like coughing, congestion, and sore throat both day and night.

Daytime Active Ingredients (in each caplet)

Acetaminophen 325 mg
Dextromethorphan HBr 10 mg
Guaifenesin 200 mg
Phenylephrine HCI 5 mg

Purpose

Pain reliever/fever reducer
Cough suppressant
Expectorant
Nasal decongestant

Inactive ingredients

carnauba wax, croscarmellose sodium, D&C yellow no. 10 aluminum lake, flavor, hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, pregelatinized starch, sucralose, titanium dioxide

Nighttime Active Ingredients (in each caplet)

Acetaminophen 325 mg
Chlorpheniramine maleate 2 mg
Dextromethorphan HBr 10 mg
Phenylephrine HCI 5 mg

Purpose

Pain reliever/fever reducer
Antihistamine
Cough suppressant
Nasal decongestant

Inactive ingredients

anhydrous citric acid, carnauba wax, FD&C blue no. 1 aluminum lake, flavor, hypromellose, magnesium stearate, microcrystalline cellulose, modified starch, polyethylene glycol, polysorbate 80, potassium sorbate, powdered cellulose, pregelatinized starch, sodium benzoate, sodium citrate dihydrate, sodium starch glycolate, sucralose, titanium dioxide.

Daytime Uses

  • for the temporary relief of the following cold/flu symptoms:
  • minor aches and pains
  • headache
  • sore throat
  • nasal congestion
  • cough
  • helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive
  • temporarily reduces fever

Nighttime Uses

  • for the temporary relief of the following cold/flu symptoms:
  • minor aches and pains
  • headache
  • sore throat
  • nasal congestion
  • cough
  • sinus congestion and pressure
  • sneezing and runny nose
  • helps clear nasal passages
  • relieves cough to help you sleep
  • temporarily reduces fever

Daytime Warnings

Liver warning: This product contains acetaminophen. The maximum daily dose of this product is 10 caplets (3,250 mg acetaminophen) in 24 hours. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
  • if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use if you have

  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland
  • persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis or emphysema
  • cough that occurs with too much phlegm (mucus)

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin

When using this product do not exceed recommended dose

Stop use and ask a doctor if

  • nervousness, dizziness, or sleeplessness occur
  • pain, nasal congestion or cough gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts

These could be signs of a serious condition.

If pregnant or breastfeeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222).Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

Nighttime Warnings

Liver warning: This product contains acetaminophen. The maximum daily dose of this product is 10 caplets (3,250 mg acetaminophen) in 24 hours. Severe liver damage may occur if you take

  • more than 4,000 mg of acetaminophen in 24 hours
  • with other drugs containing acetaminophen
  • 3 or more alcoholic drinks every day while using this product

Allergy alert: acetaminophen may cause severe skin reactions. Symptoms may include:

  • skin reddening
  • blisters
  • rash

If a skin reaction occurs, stop use and seek medical help right away.

Sore throat warning: If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.

Do not use

  • with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist.
  • if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric or emotional conditions, or Parkinson’s disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.
  • if you have ever had an allergic reaction to this product or any of its ingredients

Ask a doctor before use if you have

  • liver disease
  • heart disease
  • high blood pressure
  • thyroid disease
  • diabetes
  • trouble urinating due to an enlarged prostate gland
  • persistent or chronic cough such as occurs with smoking, asthma or emphysema
  • cough that occurs with too much phlegm (mucus)
  • a breathing problem such as emphysema or chronic bronchitis
  • glaucoma

Ask a doctor or pharmacist before use if you are

  • taking the blood thinning drug warfarin
  • taking sedatives or tranquilizers

When using this product

  • do not exceed recommended dose
  • excitability may occur, especially in children
  • marked drowsiness may occur
  • alcohol, sedatives and tranquilizers may increase drowsiness
  • avoid alcoholic drinks
  • be careful when driving a motor vehicle or operating machinery

Stop use and ask a doctor if

  • nervousness, dizziness, or sleeplessness occur
  • pain, nasal congestion or cough gets worse or lasts more than 7 days
  • fever gets worse or lasts more than 3 days
  • redness or swelling is present
  • new symptoms occur
  • cough comes back or occurs with rash or headache that lasts

These could be signs of a serious condition.

If pregnant or breastfeeding, ask a health professional before use.

Keep out of reach of children.

Overdose warning: In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.

This website contains current product information and may differ from the information on the product packaging you may have. If you have any questions, please contact the Consumer Care Center at 1-877-895-3665.

Directions

  • do not take more than directed (see overdose warning)

adults and children 12 years and older

  • take 2 caplets every 4 hours
  • swallow whole; do not crush, chew or dissolve
  • do not take more than 10 caplets in 24 hours

children under 12 years

  • ask a doctor
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Tylenol® Cold + Flu Severe Day & Night Caplets
Tylenol® Cold + Flu Severe Day & Night Caplets
Reviews (78)
Q&A (0)
Leave a Review
REVIEWS
Mydien T.
182 reviews
I always make sure to have this during cold season. It is great for symptomatic relief. You have one for daytime and one for nightime, which is great. It's one pill for all your nasty cold symptoms.
Monica B.
23 reviews
This is a must have in my medicine cabinet. I always try to stock up especially around the flu season and especially during the winter when colds are a lot more frequent, well at least it is for me. The say caplets does not make me sleepy when I take it as others do which I appreciate when I have to go into work. Would definitely recommend to keep in your medicine cabinet. 
Lauren A.
Mount Vernon, IA
882 reviews
I typically have this in my medicine cabinet and have taken it a lot this winter. I like the day because it doesn’t leave me feeling drowsy. It’s especially helpful when my cold is also leaving me with head and neck pains as well. It’s affordable and efficient.
Jake M.
Boston, MA
87 reviews
Really helps you get over that sick hump. I don't typically take products that have acetaminophen, due to high risk to liver, but if you're cautious of that this product is a Godsend. You can usually find it on some sort of sale and many coupons exist if you search Tylenol's website.
Cynthia m.
new york, NY
61 reviews
i don't understand how i never tried this product before...i recently started using this every time i get sick due to this nasty new york weather and this stuff gets me feeling much better really quick so this will be my go to for every time i get sick
Priscilla M.
San Marcos, TX
53 reviews
Being away from my mom while in college gets a little tough when you're sick which is why I'm so glad I found this medication! Every time I get sick, I run to my local drugstore & pick up a pack of these. Within a few days, I'm feeling better which is why I love this. I most definitely recommend this to everyone & their mothers!
Lisa S.
50 reviews
This works really well daytime or nighttime, nighttime is great because it takes the cold out of me and puts me to sleep. When I take them both my cold usually disappears a lot quicker and I am feeling great. I will continue to tell my family and friends to buy this and help them when they are under the weather. 
Alex M.
Massapequa, NY
425 reviews
I very rarely take Tylenol. It just wasn't the preferred pain reliever in my family growing up. I did purchase this during a rough couple of sick weeks in the winter. I don't honestly think anything really improves the way you feel, it's just like a safety blanket when you're sick. I find that the generic brands have the same effects, or lack thereof.
Karissa P.
Austin, TX
92 reviews
Tylenol knows that being sick is inconvenient. What is worse is needing to buy separate daytime and bedtime medicine which can get expensive. They combined it in this neat little package that your zombie-flu brain can figure out. It gets the job done to help manage the suffering that cold season brings
Marisa L.
Cottage Grove, MN
30 reviews
This product is one of the only things that helps me when I have a super bad cold. The daytime pills help me clear up my sinuses and help me get through the day. The night time pills help drain anything left and also let me fall asleep. I have noticed with this combo I get over my colds faster.
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