Natures Plus Ultra Lipoic delivers 500 mg of Alpha Lipoic Acid, and an additional 100 mg of R-Lipoic Acid for total body antioxidant, anti-aging nutritional support. Alpha lipoic acid is the premier rejuvenating antioxidant for the widest range of tissues. Proven effective in high energy tissues like the heart, brain, kidneys, nerves and muscles, as well as in low energy tissues, such as blood cells, connective tissues and endothelium, alpha lipoic acid is a well-rounded whole-body antioxidant. But Natures Plus takes lipoic acid supplementation to a whole new level with an additional 100 mg of R-Lipoic Acid for even greater support of high-energy tissues. Cells that need more energy make far better use of R-lipoic than any other form. R-lipoic is the form that targets free radicals in those tissues (heart, brain, kidneys, nerves and muscles), helping them function more cleanly and efficiently. The extra 100 mg of R-Lipoic antioxidant power in Natures Plus Ultra Lipoic yields an unmistakable sensation of vitality that no other lipoic acid supplement can match. For even greater synergistic activity, Natures Plus Ultra Lipoic further supplies Lactobacillus acidophilus and K12 probiotics, as well as time-honored standardized botanical extracts and proprietary full spectrum whole food blends. Revolutionary bi-layered delivery provides rapid and extended lipoic acid support for total health.