Thorne Research Phytoprofen - 60 Vegetarian Capsules Phytoprofen is a combination of botanicals, including a synergistic blend of the Ayurvedic herbs - Picrorhiza, Boswellia, and curcumin (from turmeric) - all of which support the body's normal inflammatory response. To these botanicals is added bromelain - an anti-inflammatory, protein-digesting enzyme complex from pineapple that studies have shown can reduce bruising after injury by inhibiting the production of prostaglandins and leukotrienes, as well as other chemicals involved in inflammation. The botanical extracts in Phytoprofen also can minimize post-operative / post-injury bruising and swelling without the side effects of nonsteroidal anti-inflammatory drugs (NSAIDs). Clinical research has shown bromelain reduces swelling, bruising, and pain, and speeds healing from bruises and hematomas. Supplementation with bromelain following blunt injuries to the musculoskeletal system resulted in reductions in swelling, tenderness, and pain at rest and during movement. Administration of bromelain pre-surgically can reduce the average number of days for complete disappearance of pain and inflammation. Phytoprofen provides anti-inflammatory effects while preserving cartilage, mucous membranes, and other tissues that are often damaged by over-the-counter and prescription medications. It is known that NSAIDs can cause a disruption of glycosaminoglycan synthesis that can accelerate articular damage in arthritic conditions. A recent in vivo study examined Boswellia extract for its effect on glycosaminoglycan metabolism. Glycosaminoglycans form an important component of the body's connective tissues. Boswellia significantly reduced the degradation of glycosaminoglycans compared to controls. Meriva, curcumin phytosome, demonstrates superior bioavailability compared to ordinary curcumin. Significantly greater amounts are absorbed and taken up by the liver.