I use this after applying my foundation and concealer, but before setting with face powder. I use a small synthetic brush like the elf mineral powder brush to pick up product and tap the bristles on the back of my hand to evenly distribute the blush for smoother application. For my face shape I prefer to apply blush at the top of my cheekbone, and blend out onto my cheeks.
For a dewier look, I wear this alone. Otherwise I set with a translucent powder and a big fluffy brush like the real techniques powderbleu 01 and go over with another powder blush of choice.