Solgar proudly introduces Ubiquinol 200mg (Reduced CoQ-10) Softgels. Each softgel offers 200mg of ubiquinol - the directly available, reduced form of coenzyme Q10 (ubiquinone) that may be especially useful when coenzyme Q10 has not been effective. The body converts ubiquinone to ubiquinol back and forth many times a second as it carries out its job of energy production in the mitochondria. So rather than being the "active" form of coenzyme Q10, both ubiquinone and ubiquinol are necessary. Outside of energy production in the mitochondria, the body uses an enzyme to convert ubiquinone to ubiquinol. Some individuals have a genetic variation (called a "SNP") that causes this enzyme to work much less efficiently, resulting in very low blood levels of ubiquinol and suboptimal energy production. These individuals cannot use ubiquinone well and may find that supplementation with ubiquinone is not effective for them. But ubiquinol can be easily assimilated and used since it is in the already available form and does not need conversion by the enzyme. Ubiquinol is more available in general since it is the preferred form found in the blood. Ubiquinol plays another key role as an important lipid-soluble antioxidant produced in the body. It protects the mitochondria and its lipid membranes from the abundant free radicals that are the by-products of energy production. It also protects lipids in the blood from free radical attack, including LDL cholesterol, and helps to recycle vitamin E.