Tioconazole-1. Tioconazole ointment 6.5%. Cures most vaginal yeast infections. 1 ready-to-use prefilled applicator. Compare to the active ingredient of 1-Day. (This product is not manufactured or distributed by Personal Products Company, division of McNeil-PPC, Inc, distributor of 1-Day.) This product is a 1-dose treatment, most women do not experience complete relief of their symptoms in just one day. Most women experience some relief within one day and complete relief of symptoms within 7 days. If you have questions about vaginal yeast infections, consult your doctor.