Shop for Outdoors at The Home Depot. This unique insect repellent controls over 30 common insect pests. The Safer Brand BioNEEM insecticide and repellent concentrate works as an insecticide and as a repellent. This product is formulated with azadirachtin, a natural insect growth regulator extracted from the neem seed. As an IGR, Bio-neem disrupts insects delicate hormonal balance, killing them before they molt into their next life stage. Use this natural pest control on trees, shrubs, ornamentals and flowers. Water to concentrate ratios varies per type of plant being treated. Safer Brand BioNEEM works very effectively by suffocating the insect. Remember, when using neem oil products, there is greater risk of photo toxicity (burning). Avoid using sulfur based fungicides within the active period (5-7 days) of the BioNEEM application. These two products combined, greatly increase the risk of plant burn. While Safer Brand BioNEEM is a contact killer, several applications may be needed for full control. As a general rule, much like watering, do not use these products in the peak of the day or when temperatures exceed 90 degrees F to avoid wilting or browning of the leaves. Unlike traditional synthetic chemicals, Safer Brand BioNEEM is safe to use around children and pets. It breaks down into their natural elements within 7-10 days, leaving no residual impact on the environment.