Dietary Supplement. Now Even Better! For over 10 years, ProFema™ has been the world s premiere solution for women in their transitional years. Now, because many new ingredients are available, we can make it even better. Methyl chalcone Form of Hesperidin. Five Times More Gamma Oryzonol. Expanded Botanical Base. Improved Whole Food Base. Four Tablets Instead of Six. Decreased D-Alpha Tocopheryl Succinate & Increased Mixed Tocopherol Complex for Better Balance Together, these improvements empower ProFema™ to calm midlife distress as no other supp.