Planetary Formulas Liver Defense is based on the thoroughly researched Chinese formula Minor Bupleurum, also known as Sho-Saiko-To in Japan. Modern studies show that Sho-Saiko-To supports healthy liver function and enhanced immune response. Astragalus, milk thistle, and schisandra are also included for broad-spectrum liver maintenance and protection. Lifestyle recommendations: To support liver health, avoid excessive consumption of any fatty foods, food with added chemicals, alcohol, chemical pollutants and supplement with the antioxidant N-Acetyl cysteine. Another Planetary Formulas product that support liver health is Shiitake Mushroom Supreme.