Pet Armor Pro Advanced for Dogs Pet Armor Pro Advanced Large (23-44.9 lbs),provides the same #1 veterinarian recommended active ingredient, fipronil, in the same concentration as Frontline Top Spot. You get the same flea and tick protection at a significant savings. Pet Armor Pro Advanced for Dogs acts fast. It is an effective, long lasting, waterproof, and easy to use application for killing and repelling fleas, ticks, and mosquitoes, and also killing lice on dogs and puppies eight weeks and older. When used as directed, Pet Armor Pro Advanced for Dogs stops infestations of fleas, ticks and chewing lice. This superior flea and tick preventative starts to repel within 10 minutes. Pet Armor Pro Advanced For Dogs also aids in the control of sarcoptic mange infestations. Apply monthly to eliminate sarcoptic mange mites. Directions: Fleas According to research studies, adult fleas are killed for up to three months following an application of fipronil. If, however, your dog or puppy is susceptible to flea allergy dermatitis, or if you believe there is a risk of reinfestation, apply every month. Ticks Each application kills ticks for one month or longer. For best control of ticks, apply once every month. Chewing Lice Each application kills chewing lice for one month or longer. For best control of chewing lice, apply once every month. How to Apply Squeeze the entire contents of the applicator onto the dog's skin at a single point between the shoulder blades.